Alcohol; Harmful Use

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Review clinical trials related to Alcohol; Harmful Use. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Alcohol and the Social Brain: An Alcohol-Administration Hyperscanning Study Employing a Within-Subject Design

The study investigates the effects of alcohol consumption on social and individual behaviors using a within-subject design. Participants, aged 21-30, will attend two laboratory sessions approximately one week apart, participating as part of a dyad (pair). During one session, they will consume an alcoholic beverage, while in the other, they will receive a control beverage, with the order of conditions randomized. This design facilitates direct within-participant comparisons of behaviors and neural activity in intoxicated versus sober states. To achieve these aims, the study employs EEG technology to explore intra-brain and inter-brain dynamics during social interactions. Additionally, validated self-report questionnaires will capture data on mood, social bonding, and other psychological variables. The findings are expected to enhance understanding of alcohol's role in social reward processes and contribute to developing evidence-based prevention and intervention strategies for alcohol use disorder.

Participants needed: 200
Trial details
Age: 21-30Biological sex: AllType: InterventionalSponsor: University of Illinois at Urbana-ChampaignUpdated: Aug 29, 2025Locations: 2
Eligibility criteria

Between the ages of 21 and 30 [+1]

History of adverse reaction to the amount of beverage employed in the study [+5]

Status: Recruiting

Sleep as a Mechanism of Change in Alcohol Use

This project aims to evaluate improvement of insomnia as a mechanism of improvement in alcohol use outcomes.

Participants needed: 256
Trial details
Age: 18-49Biological sex: AllType: InterventionalSponsor: University of Missouri-ColumbiaUpdated: Jul 22, 2025Locations: 1
Eligibility criteria

report heavy drinking in a typical week in the past month [+2]

≥50 years [+5]

Status: Not yet recruiting

Preventing Alcohol Use Disorders and Alcohol-Related Harms in Pacific Islander Young Adults

This study will: (1) refine and finalize the SPEAR intervention manual for preventing alcohol use disorders (AUD) and associated harms for Pacific Islander young adults; and (2) test SPEAR for efficacy by conducting a pretest-posttest randomized controlled trial (RCT).

Participants needed: 240
Trial details
Age: 18-30Biological sex: AllType: InterventionalSponsor: University of California, RiversideUpdated: Mar 29, 2024Locations: 1
Eligibility criteria

Of full or part self-reported Pacific Islander heritage; [+5]

Do not meet inclusion criteria [+3]

Status: Recruiting

Patient Trajectories for Older Adults Admitted to Hospital for Alcohol-related Problems

Alcohol is contributing to many health problems and disorders, as well as accidents and social problems. Alcohol consumption has been on the rise the past 25 years, especially in Norway. The highest increase is found in older adults, in line with the development in most other countries in the western world. Older adults have a higher risk for alcohol related health problems, due to age related physiological changes, medical conditions and medications. Still, alcohol use is seldom addressed for older people. This means that older people rarely receive help to change alcohol habits. Norwegian health authorities have issued mandates ordering the regional health trusts to implement strategies in somatic hospital wards, mental health services and drug treatment services to identify and treat alcohol and drug problems affecting the patients' health. In this observational study we will explore patient trajectories three years prior to and three years after an admittance to hospital where risky or harmful alcohol consumption is identified and brief interventions are delivered. Hospitals that have implemented such strategies are invited to the study. Patient trajectories are studied in national health registries. This will provide important knowledge on what characterizes the patients identified, and what happens after they have received a brief intervention related to a hospital admittance.

Participants needed: 500
Trial details
Age: 21+Biological sex: AllType: ObservationalSponsor: Helse Stavanger HFUpdated: Nov 24, 2023Locations: 1Duration: 3 Years
Eligibility criteria

Age 21 or older, no previous alcohol use disorder or substance use disorder, adm...

specialized treatment for alcohol use disorder og drug use disorder during the t...