Alcohol; Use, Problem

2

Review clinical trials related to Alcohol; Use, Problem. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Evaluating Signs of Safety: A Deaf-Accessible Therapy Toolkit for AUD and Trauma

The U.S. Deaf community - a group of more than one million Americans who communicate using American Sign Language (ASL) - experiences nearly triple the rate of lifetime problem drinking and twice the rate of trauma exposure compared to the general population. Although there are several treatments for alcohol use disorder (AUD) and posttraumatic stress disorder (PTSD) in hearing populations, none have been developed for or tested with Deaf clients. To address these barriers, the study team developed Signs of Safety, a Deaf-accessible therapy toolkit for treating AUD and PTSD. Their aims are to conduct a nationwide, virtual clinical trial to compare (1) Signs of Safety with (2) treatment as usual and (3) a no treatment control, to collect data on clinical outcomes, and to explore potential mediators and moderators of outcome.

Participants needed: 144
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of Massachusetts, WorcesterUpdated: Jun 15, 2026Locations: 1
Eligibility criteria

Self-identification as Deaf or hard-of-hearing [+6]

Participation in concurrent formal psychotherapy (Note: Participants in all stud... [+1]

Status: Recruiting

Using EMA Data to Inform a Web-intervention for Couples Concerned About Drinking

Alcohol misuse is a prevalent and serious problem with significant harms to society, individuals, and their relationships. Romantic partners have a strong influence on their partner's behavior, uniquely positioning them as a motivator and supportive factor in changing their partner's alcohol use, but little evidence exists on the specific ways they can influence their partner. The impact this has on the quality of their relationship, communication, and overall well-being has yet to be explored. Thus, this study utilizes qualitative, quantitative, and ecological momentary assessment (EMA) data from both partners to develop a web-based intervention that applies communication-based personalized feedback to support the concerned partner (CP) in motivating their drinking partner (DP) to reduce drinking and other adverse relationship outcomes.

Participants needed: 275
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Stanford UniversityUpdated: Apr 27, 2026Locations: 1
Eligibility criteria

be at least 18 years of age [+5]

report 4/5+ on the AUDIT-C [+6]