Alcoholic Fatty Liver Disease

1

Review clinical trials related to Alcoholic Fatty Liver Disease. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

The Efficacy of Tocotrienol Rich Fraction for Liver Protection in Adult Patients With Alcoholic Fatty Liver Disease (AFLD)

This clinical study aims to explore the potential liver-protective effects of palm tocotrienol-rich fraction (a form of Vitamin E) in adults with alcoholic fatty liver disease (AFLD). A total of 26 participants aged 18 to 65 years with AFLD will be randomly assigned to receive either tocotrienol (200 mg twice daily) or a placebo for six months. Throughout the study, participants will undergo regular liver health assessments including blood tests, FibroScan, and FibroTest, alongside evaluations of oxidative stress and inflammation markers. The study aims to determine whether tocotrienol can help improve liver function and reduce alcohol-related liver damage. Findings from this trial may provide valuable evidence for future clinical studies and highlight the potential of Malaysian palm-based tocotrienol as a natural, supportive approach to liver health.

Participants needed: 26
Trial details
Phase: Phase 2Age: 18-65Biological sex: AllType: InterventionalSponsor: Universiti Kebangsaan Malaysia Medical CentreUpdated: Apr 29, 2026Locations: 1
Eligibility criteria

Patients with history of alcoholic use disorder with clinical and biochemical ev... [+3]

Severe alcoholic hepatitis defined as Maddrey's discriminant function >32 [+19]