Status: Recruiting
Fludarabine and Intermediate-dose TBI Followed by PTCy in Patients Undergoing Allo Transplant for Heme Malignancies
The Flu-TBI 800 trial is a prospective, single-arm, multicenter, interventional phase 2 study to evaluate whether fludarabine plus intermediate-dose total body irradiation (TBI 800 cGy) with post-transplant cyclophosphamide (PTCy) (experimental regimen) improves the 1-year survival of allogeneic stem cell transplant recipients.
Participants needed: 209
Trial details
Phase: Phase 2Age: 18-65Biological sex: AllType: InterventionalSponsor: Hackensack Meridian HealthUpdated: Mar 23, 2026Locations: 3
Eligibility criteria
Patients ages 18-65 years. [+17]
Hematopoietic cell transplantation comorbidity index above 3. [+5]