Amputation Stump

2

Review clinical trials related to Amputation Stump. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Negative Pressure Wound Therapy as a Predictor of Persistent Pain After War-Related Trauma

War-related trauma frequently causes complex soft tissue injuries that require repeated surgical treatment and advanced wound management techniques such as Negative Pressure Wound Therapy (NPWT). Although NPWT is widely used to promote wound healing and prepare wounds for reconstruction, its relationship with long-term pain outcomes remains unclear. This prospective cohort study aims to investigate whether the use of NPWT after war-related trauma is associated with an increased risk of persistent post-traumatic pain six months after injury. Adult patients with traumatic soft tissue injuries requiring surgical management will be enrolled and followed for six months. In addition to NPWT exposure, the study will evaluate several early clinical predictors of chronic pain, including acute pain intensity, number of surgical debridements, suspected nerve injury, and mechanism of trauma. Understanding these predictors may help clinicians identify high-risk patients early and develop targeted strategies for pain prevention and rehabilitation after severe trauma.

Participants needed: 150
Trial details
Age: 18-60Biological sex: AllType: ObservationalSponsor: Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)Updated: Mar 18, 2026Locations: 1
Eligibility criteria

age ≥18 years [+4]

chronic pain in the same anatomical region prior to injury [+4]

Status: Not yet recruiting

Comparison Between Digital Nerve Microanastomosis and Traction Neurectomy in Post-Digital Amputation Pain

The goal of this prospective observational study is to assess the post-operative pain in adults with digital amputation following two different surgical interventions: microanastomosis of digital nerves or traction neurectomy. The main questions it aims to answer are: * Which surgical intervention results in less post-operative pain? * Which surgical intervention leads to fewer symptoms after six months? * Which surgical intervention is associated with fewest post-operative complications? Participants will complete a Visual Analog Scale (VAS) to assess the pain and the Disabilities of the Arm, Shoulder and Hand Questionnaire (DASH) to evaluate the disabilities. The researchers will assess post-operative complications during follow-up appointments.

Participants needed: 50
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Centre hospitalier de l'Université de Montréal (CHUM)Updated: Sep 15, 2025
Eligibility criteria

Age ≥ 18 years [+3]

Patients treated with a surgical intervention other than microanastomosis of dig... [+3]