Amputation; Traumatic, Leg: Thigh, Between Hip and Knee

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Review clinical trials related to Amputation; Traumatic, Leg: Thigh, Between Hip and Knee. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Effects of Microprocessor-controlled Prosthetic Knees on Fall-related Health Outcomes in Limited Community Ambulators

The goal of this study is to find out if using microprocessor-controlled prosthetic knees (MPKs), prosthetic knees with a built-in computer, improves health outcomes related to falls in adults who use above-knee prostheses. The main questions are: * Do individuals with MPKs have fewer fall-related health issues compared to those with non-microprocessor-controlled prosthetic knees (nMPKs)? * Do individuals with MPKs have increased mobility, faster walking speed, and improved quality of life compared to those with nMPKs? Participants who have recently received an nMPK as part of their regular care can join the study. Those randomized to the control group will keep using their nMPK, while those randomized to the intervention group will receive a stance-and-swing MPK or a stance-only MPK.

Participants needed: 100
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Hanger Institute for Clinical Research and Education, LLCUpdated: Feb 5, 2026Locations: 1
Eligibility criteria

Unilateral transfemoral or knee disarticulation limb loss. [+8]

Any health condition that would prevent safely completing trial activities. [+4]

Status: Recruiting

Clinical Outcomes With Non-Powered vs. Powered Prosthetic Knees by K2-level Amputees

The goal of this proposed project is to gather community-based data from the K2-level Transfemoral Amputee (TFA) population to aid in evidence-based prescription of powered prosthetic knees (i.e., choosing the right device to maximize the benefit for each patient). The investigators intend to use this trial data along with a concurrent study being conducted within the K3-K4 level population to guide the implementation of effective prescriptions towards those that can benefit most from a given device and limit prescription to those who would not see benefit in order to ensure the most judicious use of Department of Defense (DoD) and Veteran's Affairs healthcare dollars. The findings will also be shared with the research community to help drive the design of future devices by identifying what features and functions are most beneficial to which patient populations when the devices are used outside of the laboratory. In summary, more community-based data on how powered prosthetic knees compare with the current standard in TFA populations is needed to allow for improved clinical decision making and clinical outcomes.

Participants needed: 26
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Liberating Technologies, Inc.Updated: Sep 3, 2025Locations: 1
Eligibility criteria

Are at least 18 years old [+10]

Present injuries to residual limb or contralateral leg affecting functional abil... [+4]