Health Trials

Anaplastic Meningioma

2

Review clinical trials related to Anaplastic Meningioma. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms

The primary objective of this Phase 1, open-label, dose-escalation, and exploratory study is to evaluate the safety and tolerability profile (establish the maximum-tolerated dose) and evaluate the occurrence of dose-limiting toxicities (DLTs) following single weekly or multiple-day weekly dose regimens of single-agent, oral ONC206 in patients with recurrent, primary central nervous system (CNS) neoplasms.

Participants needed: 102
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Jazz PharmaceuticalsUpdated: Dec 18, 2025Locations: 1
Eligibility criteria

Patients aged ≥18 years with a recurrent, primary CNS neoplasm. For all cohorts,... [+21]

(Exclusion Criterion #1 was removed in Amendment 3) [+33]

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Status: Recruiting

Predictive Factors for Survival in Aggressive Meningiomas

The investigators plan to collect clinical and molecular data, including ICH, PCR, NGS and methylome, from patients operated on for grade 2 or grade 3 meningioma. The purpose of the study is to identify reliable and easy-to-assess predictive factors for recurrence and survival after surgery.

Participants needed: 250
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCSUpdated: Mar 13, 2025Locations: 1
Eligibility criteria

Patient operated for atypical (grade 2) meningioma; or [+2]

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