Ankyloglossia

2

Review clinical trials related to Ankyloglossia. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Healing Efficacy of Diode Laser in Lingual Frenectomy

This study aims to compare the wound healing efficacy and postoperative experiences between the 940 nm diode laser technique and the traditional electrosurgery method for treating ankyloglossia (tongue-tie) in children aged 3 to 6 years. Participants are randomly assigned to one of two groups: Experimental Group - Patients undergo lingual frenectomy using a 940 nm diode laser and Active Comparator Group - Patients undergo the procedure using conventional high-frequency electrosurgery. The study evaluates several key outcomes at multiple intervals (24 hours, 3 days, 1 week, and 1 month post-surgery), including: (1) Wound Healing: Measured by the Early Wound Healing Score (EHS); (2) Pain Levels: Assessed using the Wong-Baker FACES Pain Rating Scale; (3) Bleeding Control: Evaluation of intraoperative bleeding; (4) Tongue Mobility: Measurement of free tongue length according to Kotlow's classification. The goal is to determine if the diode laser provides superior healing, less pain, and better bleeding control compared to electrosurgery.

Participants needed: 53
Trial details
Age: 3-6Biological sex: AllType: InterventionalSponsor: University of Medicine and Pharmacy at Ho Chi Minh CityUpdated: Apr 30, 2026Locations: 2
Eligibility criteria

Patients aged between 3 and 6 years. [+3]

History of allergy to local anesthetics (e.g., Lidocaine, Adrenaline). [+3]

Status: Recruiting

Post-Procedural Manual Manipulation for Infant Ankyloglossia

The goal of this randomized control trial is to determine the impact of post-frenotomy manual manipulation on revision rates and breastfeeding outcomes. We hypothesize that post-frenotomy manipulation will reduce the rate of sublingual frenulum regrowth, and subsequently frenotomy revision rates, thereby improving breastfeeding performance. Infants with ankyloglossia undergoing frenotomy will be randomized into two groups: the intervention group (post-frenotomy manipulation) and the control group (no intervention). Parents in the intervention group will be instructed to perform tongue stretching and suck "re-training" exercises four times daily for 2-3 weeks, beginning 24 hours post-procedure. To monitor adherence and assess any complications, investigators will conduct a follow-up phone call one week after the procedure. Parents in the control group will not be instructed to perform any post-procedural manipulation. All participants will have a mandatory in-person follow-up 2-3 weeks postoperatively, during which breastfeeding outcomes and the need for frenotomy revision will be evaluated.

Participants needed: 110
Trial details
Age: Up to 90Biological sex: AllType: InterventionalSponsor: Georgetown UniversityUpdated: Feb 17, 2025Locations: 1
Eligibility criteria

infants less than 90 days old with ankyloglossia who undergo outpatient frenotom...

infants older than 90 days, those who will be exclusively bottle fed, infants wh... [+1]