Status: Recruiting
Pharmacokinetics Of Emulsified Avacopan Applied By NG Tube
The purpose of this study is to determine the 72-hour pharmacokinetics of emulsified avacopan at a dose of 30 mg twice daily given to up to 6 patients with active severe GPA or MPA with diffuse alveolar hemorrhage (DAH) requiring mechanical ventilation for respiratory support.
Participants needed: 6
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Mayo ClinicUpdated: Apr 29, 2026Locations: 1
Eligibility criteria
Fulfillment of the definitions of the Second Chapel Hill Consensus Conference fo... [+6]
Diagnosis with eosinophilic granulomatosis with polyangiitis (EGPA, formally Chu... [+8]