Status: Recruiting
Adaptive Dengue Antiviral Platform Trial
This is a randomized, open-label adaptive platform trial aiming to screen the antiviral effectiveness of the experimental drug(s) in early dengue infection * Primary objectives: * To determine the antiviral effectiveness of the experimental drug(s) in early dengue infection * To assess the safety and tolerability of the experimental drug(s) in dengue patients * Secondary objective: * To assess the effect of the experimental drug(s) in dengue patients on physiological, clinical and virological parameters
Participants needed: 500
Trial details
Phase: Phase 2Age: 10+Biological sex: AllType: InterventionalSponsor: Oxford University Clinical Research Unit, VietnamUpdated: Apr 30, 2026Locations: 2
Eligibility criteria
Female or male patients with a clinical diagnosis of dengue virus infection and... [+4]
Meets criteria for severe dengue at baseline (severe plasma leakage leading to d... [+8]