Aortic Intramural Hematoma

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Review clinical trials related to Aortic Intramural Hematoma. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

AAR/AAR+HAR vs AAR+TAR+FET for Type A Aortic Intramural Hematoma

This is a prospective, randomized, non-inferiority clinical trial designed to compare the efficacy and safety of two surgical strategies for acute type A aortic intramural hematoma (TAIMH): (1) ascending aorta replacement or ascending aorta plus hemiarch replacement (AAR/AAR+HAR), and (2) ascending aorta replacement with total arch replacement and frozen elephant trunk implantation (AAR+TAR+FET). Patients will be enrolled based on CTA confirmation of a completely thrombosed false lumen in the ascending aorta and aortic arch. Eligible participants will be randomized in a 1:1 ratio to either group. The primary endpoint is the rate of reintervention on the aortic arch or descending aorta from 6 to 12 months after surgery. Secondary endpoints include circulatory arrest time, aortic cross-clamp time, major adverse cardiovascular events, other perioperative complications, and total hospitalization cost. A total of 400 participants will be enrolled.

Participants needed: 400
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: Second Hospital of Jilin UniversityUpdated: May 8, 2026
Eligibility criteria

Age ≥ 18 years and ≤ 80 years. [+2]

Preoperative CTA shows an open or partially thrombosed (mixed) false lumen in th... [+7]