Apnea, Obstructive Sleep

2

Review clinical trials related to Apnea, Obstructive Sleep. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

OSA-18 in Children With Mild Obstructive Sleep Apnea: Can it be a Helpful Decision Making Tool?

The concept is a novel research idea that incorporates the potential impact of patient quality of life (QOL) on decision-making for treatment of mild obstructive sleep apnea (OSA). Our hypothesis is that in children with mild OSA there is significant conflict with parental decision-making; in the absence of significant sleep apnea, there is limited research regarding comparative efficacy of various treatment options. The impact of a QOL questionnaire can be a significant deciding factor and may help guide management decisions in such situations.

Participants needed: 130
Trial details
Age: 3-12Biological sex: AllType: InterventionalSponsor: Connecticut Children's Medical CenterUpdated: May 28, 2026Locations: 1
Eligibility criteria

Parent/caregiver of child with an initial diagnosis mild obstructive sleep apnea... [+2]

Parent/caregiver of child diagnosed with a syndromic or known neurologic conditi... [+1]

Status: Not yet recruiting

CPAP in Patients With Severe Obesity After Anesthesia

The goal of this study is to compare two continuous positive airway pressure (CPAP) settings on heart and lung function in patients with severe obesity after anesthesia. The main questions it aims to answer are: 1. Does a recruitment maneuver and CPAP set to intrathoracic pressure (ITP) improve cardiopulmonary function compared to standard CPAP settings in patients with severe obesity after anesthesia? 2. Does the location of adipose tissue influence the response to CPAP settings in patients with severe obesity after anesthesia? Participants will undergo monitoring of their intrathoracic pressure using an esophageal catheter. In the recovery area after anesthesia, participants will receive two CPAP settings, each for 20 minutes. * Intervention 1: Recruitment maneuver and CPAP will set to the level of intrathoracic pressure * Intervention 2: CPAP set to home settings (if OSA is present) or between 8-10 cmH20 (if OSA is not present).

Participants needed: 60
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Massachusetts General HospitalUpdated: Nov 18, 2025
Eligibility criteria

Adult patients (≥ 18 years old) scheduled for elective non-cardiothoracic surger... [+5]

Pregnancy, suspected pregnancy or less than six weeks postpartum Known or curren... [+16]