Status: Not yet recruiting
A Nutritional Intervention for Body, Brain, and Longevity Effects (NIBBLE)
The study aims to evaluate the safety, feasibility, and preliminary efficacy of six-month fasting-mimicking (FMD) relative to Dietary Guidance intervention in middle-aged adults at elevated risk for Alzheimer's disease due to the apolipoprotein (APOE) ε4 allele. Participants randomly assigned to the FMD intervention will consume a FMD for 5-days each month over a period of 6-months.
Participants needed: 40
Trial details
Age: 45-65Biological sex: AllType: InterventionalSponsor: Cedars-Sinai Medical CenterUpdated: Feb 9, 2026Locations: 1
Eligibility criteria
Provision of signed and dated informed consent form [+5]
Has any medical disease or condition that, in the opinion of the principal inves... [+19]