Health Trials

ARID1A Gene Mutation

2

Review clinical trials related to ARID1A Gene Mutation. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

JAB-2485 Activity in Adult Patients With Advanced Solid Tumors

This study is to evaluate the safety and tolerability of JAB-2485 monotherapy in adult participants with advanced solid tumors.

Participants needed: 102
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Jacobio Pharmaceuticals Co., Ltd.Updated: Jan 9, 2026Locations: 8
Eligibility criteria

Must have Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1 [+7]

Has central nervous system (CNS) metastases or carcinomatous meningitis, except... [+7]

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Status: Recruiting

Avelumab and M1774 in ARID1A-mutated Endometrial Cancer

The purpose of this research study is to see if the combination of study drugs avelumab and M1774 is effective and safe for participants with endometrial cancer. The names of the study drugs involved in this study are: * Avelumab (a type of human IgG1 antibody) * M1774 (a type of ATR inhibitor)

Participants needed: 25
Trial details
Phase: Phase 2Age: 18+Biological sex: FemaleType: InterventionalSponsor: Panagiotis Konstantinopoulos, MD, PhDUpdated: Jan 7, 2026Locations: 2
Eligibility criteria

Participants must have endometrial cancer that is ARID1A-mutated [loss of functi... [+15]

Participants who have had chemotherapy, immunotherapy, other investigational the... [+24]

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