Artificial Intelligence

56

Review clinical trials related to Artificial Intelligence. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Ambient Audio-Visual Capture for Clinical Documentation and Assessment

AI-powered tools that automatically document clinical conversations are being adopted rapidly in outpatient settings but have not been evaluated in hospital wards. Existing tools use audio recording only, which cannot capture physical examination findings, procedural observations, or clinical safety behaviours - elements of a ward round that are visible but not audible. This study evaluates an ambient audio-visual (AV) capture system - BlackFrame - that uses both microphone and camera to generate accurate clinical documentation and structured educational feedback in a real inpatient surgical ward setting. Medical students and doctors in training participate in supervised ward round encounters with consenting adult inpatients. The BlackFrame AI platform generates: (a) a structured draft clinical note for the supervising clinician to review and countersign before any use in the patient record; and (b) formative feedback for the trainee, delivered within 30 minutes, covering clinical communication, examination technique, and documentation quality. The study measures whether AI-generated feedback improves trainee clinical performance over a placement, how much documentation time is saved, and whether the system is acceptable to patients and clinicians. No AI-generated text enters the patient record without explicit clinician review and sign-off. All participation is voluntary.

Participants needed: 60
Trial details
Biological sex: AllType: InterventionalSponsor: BlackFrame.aiUpdated: Jun 16, 2026
Eligibility criteria

Doctor in training (FY1 through registrar/ST grade) undertaking a supervised cli... [+14]

Status: Not yet recruiting

The Effect of AI-Assisted Nursing Process Training on Nursing Process Competence, Perception and Attitudes Towards Artificial Intelligence in Nurses: A Randomized Controlled Study

This study aims to determine how applied artificial intelligence (AI) training affects nurses' ability to manage the nursing process and their perceptions and attitudes toward AI technology * The nursing process is a scientific, six-stage approach used by nurses to identify patient needs and provide holistic care The research is a randomized controlled trial involving 78 nurses at Yalova Education and Research Hospital . Participants will be split into two groups: Both groups will receive standard theoretical training on the nursing process . The intervention group will receive additional specialized training on using AI tools (such as ChatGPT and Deepseek) to help create nursing care plans through practical case studies . Nurses' skills and views will be measured using specific scales before the training and one month after the intervention to evaluate the training's effectiveness * This study is expected to provide valuable insights into how AI can support clinical decision-making and help healthcare providers adapt to new technologies * The research has been approved by the Yalova University Ethics Committee (Protocol 2026/183) and will be conducted between May and December 2026

Participants needed: 78
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of YalovaUpdated: Jun 1, 2026Locations: 1
Eligibility criteria

Volunteering to participate in the study. [+2]

Refusing to participate in the study. [+2]

Status: Recruiting

AI-TOP Study Artificial Intelligence for Trigger Optimization.

To evaluate, in a randomized controlled trial, whether AI-guided monitoring and ovulation triggering leads to clinical outcomes comparable to those achieved through physician-led decision-making in patients undergoing ovarian stimulation for IVF.

Participants needed: 644
Trial details
Age: 18-42Biological sex: FemaleType: InterventionalSponsor: Fundacion DexeusUpdated: Apr 22, 2026Locations: 5
Eligibility criteria

Undergoing COS for IVF with autologous oocytes, oocyte donation and elective fer...

Medically indicated fertility preservation [+1]

Status: Not yet recruiting

AI-Assisted Workflow for Occult Atrial Fibrillation Detection After Ischemic Stroke: A Prospective Randomized Trial

We hypothesize that an AI-guided AF risk stratification approach, particularly when combined with intensified rhythm monitoring using wearable devices and extended ECG patches, will significantly increase AF detection rates compared with standard care. By enabling earlier identification of patients who may benefit from anticoagulation therapy, this strategy has the potential to improve clinical outcomes while minimizing unnecessary exposure to anticoagulant-related bleeding risks. Ultimately, this trial seeks to provide robust clinical evidence supporting the integration of AI-assisted ECG analysis into routine post-stroke care, advancing precision medicine and optimizing resource allocation for patients with ischemic stroke.

Participants needed: 400
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: National Taiwan University HospitalUpdated: Apr 20, 2026Locations: 1
Eligibility criteria

18 years or older who are acutely hospitalized due to ischemic stroke; [+1]

Previous diagnosis of atrial fibrillation or flutter; [+6]

Status: Not yet recruiting

AI-based Informational Assistant for Automated Point-of-care Documentation and Protocol Retrieval

Clinical rounds in the intensive care unit (ICU) involve substantial manual documentation. Retrieving the correct protocol text and structuring notes at the bedside is time-consuming and may contribute to variation in documentation quality. Modern artificial intelligence (AI) can help structure existing information and automate protocol look-ups within a restricted, manually selected document set. The tool evaluated in this study acts as an AI-based informational assistant for clinicians. It (1) pre-populates a standardized physical-exam and daily-rounds format, (2) prepares a concise ICU course/overview using predefined formatting, and (3) retrieves relevant passages from protocols to enable rapid consistency checks by the clinician. The AI-based informational assistant does not provide treatment recommendations or patient-specific advice; all outputs require clinician verification and clinical responsibility remains with the physician.

Participants needed: 25
Trial details
Biological sex: AllType: ObservationalSponsor: Willemijn BerkhoutUpdated: Mar 25, 2026
Eligibility criteria

ICU physician (nurse practicioner, resident, or staff intensivist) at the Erasmu... [+1]

Status: Recruiting

Adverse Outcome of Acute Pulmonary Embolism by Artificial Intelligence System Based on CT Pulmonary Angiography

The investigators aim to build a predictive tool for Adverse Outcome of Acute Pulmonary Embolism by Artificial Intelligence System Based on CT Pulmonary Angiography.

Participants needed: 2,000
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Shengjing HospitalUpdated: Mar 11, 2026Locations: 1
Eligibility criteria

age of ≥ 18 years and a pulmonary embolism diagnosis based on CT pulmonary angio...

pregnancy [+2]

Status: Not yet recruiting

BaiXiaoAi AI Companion for Cancer Patient Follow-up

This is a prospective, single-center, exploratory study designed to evaluate the accuracy, user engagement, and user experience of the BaiXiaoAi Companion AI. Upon signing the informed consent form and enrollment, a dedicated "Doctor-Nurse-Patient-AI" WeChat group will be established for each participant. Within the group, the BaiXiaoAi AI will provide timely responses based on patient communications and proactively push information regarding disease management and patient education.

Participants needed: 300
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Cancer Institute and Hospital, Chinese Academy of Medical SciencesUpdated: Feb 9, 2026Duration: 6 Months
Eligibility criteria

Adults aged 18 years or older; [+3]

Presence of severe psychiatric disorders (e.g., schizophrenia, bipolar disorder)... [+2]

Status: Recruiting

Locally Optimised Contouring With AI Technology for Radiotherapy

LOCATOR is a multicentre phase II randomised clinical trial that is looking at the process of contouring in radiation treatment for breast cancer patients. This study looks at whether contouring aided by artificial intelligence (AI) is comparable in quality to that of contouring done completely manually by a radiation oncologist. We are also looking at whether AI assisted contouring saves radiation oncologists time when compared to fully manual contouring. LOCATOR uses the LOCATOR software which is an in-house software developed locally and trained on local data.

Participants needed: 444
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Royal North Shore HospitalUpdated: Jan 29, 2026Locations: 3
Eligibility criteria

18 years and older who are planned for primary breast malignancy [+3]

Patients under 18 years of age [+1]

Status: Not yet recruiting

Optimization of Medical Time in the Emergency Department: Impact of an AI-Based System on Prescription Entry

Drug-related iatrogenesis is a major public health issue, accounting for a significant proportion of adverse events and hospitalizations in emergency departments. Optimizing prescription management in this context is critical to improve both patient safety and physician efficiency This study aims to evaluate the impact of the POSOS AI-driven device on the medical time required for prescription management in polymedicated patients admitted to emergency departments. The main objective is to establish whether the use of POSOS can reduce transcription time compared to standard electronic management.

Participants needed: 770
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Centre Hospitalier Universitaire, AmiensUpdated: Jan 8, 2026Locations: 1
Eligibility criteria

Age ≥18 years [+3]

Patient under legal protection/judicial measures (guardianship/custody) [+1]

Status: Recruiting

The Relationship Between Quality of Life, Anxiety Levels, and Attitudes Toward Artificial Intelligence Among Women Undergoing Infertility Treatment

Infertility affects approximately one in six individuals worldwide and is associated with significant psychological distress, particularly among women undergoing treatment. Increased anxiety levels are strongly linked to reduced quality of life during the infertility process. With the growing integration of artificial intelligence (AI) into healthcare, AI-based tools are increasingly used in infertility care to support decision-making and patient engagement. While many patients are familiar with AI technologies, individual attitudes toward AI may influence their acceptance and potential psychosocial benefits. This study aims to examine the relationship between attitudes toward artificial intelligence, anxiety levels, and quality of life among women undergoing infertility treatment.

Participants needed: 191
Trial details
Age: 18-45Biological sex: FemaleType: ObservationalSponsor: Acibadem UniversityUpdated: Dec 29, 2025Locations: 1
Eligibility criteria

Women aged 18-45 years diagnosed with infertility (primary or secondary infertil... [+3]

Women with diagnosed psychological disorders (e.g., clinical depression, anxiety... [+1]

Status: Not yet recruiting

Real-time Feedback of Red-out Within Colonoscopy Intubation

This study will employ a prospective, multicenter, controlled design. It will be conducted across multiple centers, with participated centers randomly assigned to one of four groups: Group A, Group B, Group C, and Group D. The research will primarily focus on the AI-based analysis of colonoscopic images to calculate the following metrics: caecal intubation time, red-out percentage, and the AI-based red-out avoiding score. Based on the study's implementation protocol, a decision will be made regarding whether to provide real-time feedback. Additionally, the presence of any complications will be assessed both during and after the colonoscopy procedure.

Participants needed: 576
Trial details
Age: 18-70Biological sex: AllType: InterventionalSponsor: The First Affiliated Hospital of Anhui Medical UniversityUpdated: Dec 10, 2025
Eligibility criteria

Not listed

Status: Recruiting

Artificial Intelligence in Assessing Gastric Intestinal Metaplasia Via the EGGIM Score

The endoscopic grading system (EGGIM) has been widely used to assess the extent of gastric intestinal metaplasia during endoscopy. Investigators developed an artificial intelligence (AI) system to automatically evaluate the extent of gastric intestinal metaplasia (GIM) and calculate the EGGIM scores in endoscopy examination. This study is a prospective, multi-center study aimed at exploring the performance and reliability of AI-EGGIM scoring. This is a prospective study designed to validate the AI-EGGIM system in a larger cohort. The study protocol was developed based on preliminary experience from a prior investigation (NCT05464108).

Participants needed: 3,000
Trial details
Age: 40-75Biological sex: AllType: ObservationalSponsor: Qilu Hospital of Shandong UniversityUpdated: Dec 2, 2025Locations: 3
Eligibility criteria

patients aged 40-75 years who undergo the IEE examination [+1]

patients with severe cardiac, cerebral, pulmonary or renal dysfunction or psychi... [+1]

Status: Recruiting

Miss Rate of Gastric Neoplasms Under Computer-aided Endoscopy

This prospective randomized trial compares AI-assisted upper gastrointestinal endoscopy with high definition upper gastrointestinal endoscopy in term of missed rate of gastric neoplasm. The investigators hypothesize the miss rate of high definition upper gastrointestinal endoscopy is higher than AI-assisted upper gastrointestinal endoscopy.

Participants needed: 1,000
Trial details
Age: 40+Biological sex: AllType: InterventionalSponsor: The University of Hong KongUpdated: Nov 20, 2025Locations: 1
Eligibility criteria

Patients aged 40 or older [+1]

Pregnant women, [+3]

Status: Not yet recruiting

Glioma Adaptive Radiotherapy With Development of an Artificial Intelligence Workflow

Gliomas are common primary brain tumors in adults. Gliomas can be classified into different types based on tumor grade, histopathological features, and molecular characteristics. The common types of diffuse gliomas include glioblastoma, astrocytoma, and oligodendroglioma. The standard treatment for diffuse gliomas includes surgery followed by radiation and chemotherapy. As per standard institutional practice, a uniform dose of radiation is delivered to the disease area and MRI is done before and after the treatment. In this study, MRI and PET scan will be done before starting the treatment and standard dose of radiation will be delivered. The interval imaging will be done twice during the course of treatment with MRI and PET, followed by dose modifications. The CT, MRI, and PET will be combined. Based on PET imaging, specific dose will be altered and delivered to specific areas. Dose modification will be done with the help of artificial intelligence. Participant's assessment will be done at regular intervals. Modifications in radiation plans are done based on the changes in disease seen in scans is likely to improve the accuracy of RT treatments. Dose modifications based on imaging to resistant areas will help achieve better tumor control, reduce treatment-related toxicities, precise delivery of the RT and adjusting doses to the organs at risk (OAR) and changes in disease leading to better treatment compliance. Creating an artificial intelligence framework in radiation oncology promises to improve quality of workflow, treatment planning and RT delivery. The aim of the study is to develop an artificial intelligence workflow for treatment of glioma with adaptive radiotherapy. This study will be conducted in Tata Memorial Centre on a population of 60 patients for a duration of 2 years. The total study duration is 4 years.

Participants needed: 60
Trial details
Phase: Phase 2Age: 18-70Biological sex: AllType: InterventionalSponsor: Tata Memorial CentreUpdated: Sep 16, 2025
Eligibility criteria

Histological diagnosis of diffuse glioma. Patients with IDH-negative GBM (stratu...

Multifocal or multicentric disease Not eligible for radical intent radiation. ID...

Status: Not yet recruiting

AI Toothbrush and Visual Pedagogy to Improve Oral Hygiene in Children With Autism Spectrum Disorder

This randomized clinical trial evaluates the effectiveness of an AI-enabled electric toothbrush and visual pedagogy materials in improving oral hygiene among children with autism spectrum disorder (ASD). The study compares plaque control, gingival health, and adherence between children using a manual toothbrush with visual pedagogy support and those using an AI-enabled electric toothbrush with app-based monitoring.

Participants needed: 50
Trial details
Age: 5-13Biological sex: AllType: InterventionalSponsor: University of Sao PauloUpdated: Sep 8, 2025Locations: 1
Eligibility criteria

Not listed

Status: Not yet recruiting

Multimodal Radiology Report to Improve Patient-centered Radiology

The goal of this study is to learn if AI-generated video explanations help people better understand their radiology reports. The main question it aims to answer is: Do AI-generated videos help participants understand their medical imaging results better than written reports alone? Participants will send their own radiology images and written reports to the research team; receive a personalized AI-generated video that explains their results in easy-to-understand language; watch their video explanation (about 1-5 minutes long); and complete 15-minute online survey about how well the video helped them understand their results.

Participants needed: 200
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Harvard Medical School (HMS and HSDM)Updated: Sep 8, 2025
Eligibility criteria

Age 18+ adults who have taken a radiology examination.

N/A

Status: Recruiting

Assessment of Liver Diseases Using a Deep-Learning Approach Based on Ultrasound RF-Data

The goal of this clinical trial is to test the performance of neuronal networks trained on ultrasonic raw Data (=radiofrequency data) for the assessment of liver diseases in patients undergoing a clinical ultrasound examination. The general feasibility is currently evaluated in a retrospective cohort. The main questions the study aims to answer are: * Can a neuronal network trained on RF Data perform equally good as elastography in the assessment of diffuse liver diseases? * Can a neuronal network trained on RF Data perform better than a neuronal network trained on b-mode images in the assessment of diffuse liver diseases? * Can a neuronal network trained on RF Data distinguish focal pathologies in the liver from healthy tissue? To answer these questions participants with a clinically indicated fibroscan will undergo: * a clinical elastography in Case ob suspected diffuse liver disease * a reliable ground truth (if normal ultrasound is not sufficient e.g. contrast enhanced ultrasound, biopsy, MRI or CT) in case of focal liver diseases, depending on the standard routine of the participating center * a clinical ultrasound examination during which b-mode images and the corresponding RF-Data sets are captured

Participants needed: 200
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Technische Universität DresdenUpdated: Aug 20, 2025Locations: 4
Eligibility criteria

scheduled for an ultrasound investigation by an independent physician [+1]

smaller interventions in the same liver during the last 2 Week (for example live... [+2]

Status: Recruiting

Augmented Endobronchial Ultrasound (EBUS-TBNA) With Artificial Intelligence

To evaluate the usefulness of Deep neural network (DNN) in the evaluation of mediastinal and hilar lymph nodes with Endobronchial ultrasound (EBUS). The study will explore the feasibility of DNN to identify lymph nodes and blood vessel examined with EBUS.

Participants needed: 50
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Norwegian University of Science and TechnologyUpdated: Aug 22, 2025Locations: 2
Eligibility criteria

Subjects referred to thoracic department in any of the participating hospitals w... [+1]

Pregnancy [+1]

Status: Recruiting

Artificial Intelligence for Pathology Diagnosis and Prognosis Prediction of Lung Nodule Using Smartphone Photos

The current study aims to develop and validate a deep learning signature for diagnosing pathology and predicting prognosis of lung nodule using smartphone photos of resected tumor specimens.

Participants needed: 600
Trial details
Age: 20-75Biological sex: AllType: ObservationalSponsor: Anhui Provincial HospitalUpdated: Aug 1, 2025Locations: 3
Eligibility criteria

Not listed

Status: Recruiting

A Real-world Study of the Efficacy and Safety of ICIs as First-line Therapy for Advanced Malignancies

In this study, we collected the data of immunohistochemistry, gene detection, image, OS, PFS, Orr, and so on. Secondly, the database of immunotherapy for malignant tumor was established, and the predictive model was constructed to verify and establish the rationality and validity of the biomarkers and predictive system of immunotherapy

Participants needed: 120
Trial details
Age: 18-75Biological sex: AllType: ObservationalSponsor: Xinqiao Hospital of ChongqingUpdated: Jul 14, 2025Locations: 1
Eligibility criteria

Informed consent has been signed and, in the judgment of the investigator, the p... [+5]

the patients' compliance was poor, which violated the rules of the trial; [+3]

Status: Recruiting

Assisting Pulmonary Disease Diagnosis With Ophthalmic Artificial Intelligence Technology

This study intends to collect ophthalmologic examination results, pulmonary examination results and related indexes from patients with pulmonary disease and control populations, and combine big data analysis and artificial intelligence technology to explore whether new methods can be provided for early screening strategies for pulmonary disease with the aid of ophthalmologic examination, and thus assist in identifying the types of pulmonary disease and determining disease prognosis.

Participants needed: 10,000
Trial details
Biological sex: AllType: ObservationalSponsor: Zhongshan Ophthalmic Center, Sun Yat-sen UniversityUpdated: May 23, 2025Locations: 4
Eligibility criteria

Those aged ≥18 years; or those aged <18 years who can cooperate with the relevan... [+6]

Patients who are unable to complete ophthalmology or pulmonary-related examinati... [+3]

Status: Recruiting

Research on Early Prediction Model of Ischemic Cerebrovascular Disease Based on Artificial Intelligence Technology.

Establish an artificial intelligence clinical decision support system for patients with carotid/vertebral artery cerebrovascular stenosis, early identification of patients who may have cerebral infarction. With the support of this project, it is expected that a secondary prevention clinical decision support system for chronic stroke will be established, which is likely to become an important auxiliary tool for the management of cerebrovascular diseases in the future.

Participants needed: 244,296
Trial details
Biological sex: AllType: ObservationalSponsor: Shanghai Jiao Tong University School of MedicineUpdated: May 18, 2025Locations: 1
Eligibility criteria

Not listed

Status: Recruiting

Evaluating an AI-Generated Health Podcast

This study aims to explore a new way of delivering health information using an AI-generated podcast. The podcast, created with Google NotebookLM, uses verified content from the American Academy of Periodontology website to provide easy-to-understand information on gum health and prevention. The goal is to determine whether this AI-generated podcast is a useful, engaging, and clear tool for educating the general public about health topics. Traditional health podcasts often feature expert interviews and can be lengthy, which sometimes limits their appeal and accessibility. By using AI to generate the podcast, investigator hope to offer a more standardized and concise presentation that avoids technical jargon. To evaluate the podcast, investigator developed a questionnaire based on the Questionnaire for Assessing Educational Podcasts (QAEP). This questionnaire was adapted to better suit a non-specialist audience and covers four key areas: how easy the podcast is to access and use, the design and structure of the podcast, the clarity and completeness of the content, and the podcast's value as a learning tool. Before using this questionnaire with the general public, investigator sent it to 10 experts in dentistry, public health, and communication for their review and feedback. Their input helped us make minor modifications to ensure the questionnaire is both clear and scientifically sound. After these revisions, investigator conducted a pilot study with 30 members of the general public who listened to the podcast and completed the questionnaire. This study will assess the feasibility and validity of using an AI-generated podcast as a health education tool. The results will help determine if this approach can effectively improve public understanding of health information and may guide the future design of digital health communication strategies.

Participants needed: 30
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Qassim UniversityUpdated: Mar 26, 2025Locations: 1
Eligibility criteria

Licensed professionals and recognized experts in relevant fields such as dentist... [+4]

Professionals without formal training or relevant expertise in the specified fie... [+9]

Status: Not yet recruiting

ChatGPT-Assisted Hypertension Knowledge in Nursing Students

ChatGPT provides quick access to information, research support, and study materials, but concerns remain regarding its reliability, accuracy, and inability to offer personalized care principles essential in nursing. Although previous studies show its high accuracy in clinical responses, over-reliance on AI-generated medical information necessitates cautious use. The study will explore both the benefits and limitations of ChatGPT in nursing education, particularly in hypertension learning.

Participants needed: 96
Trial details
Biological sex: AllType: InterventionalSponsor: Ankara UniversityUpdated: Mar 7, 2025
Eligibility criteria

To be enrolled in the nursing program at a private university, during the 2024-2... [+2]

Students who wish to withdraw from the research at any stage will not be include...

Status: Recruiting

Artificial Intelligence (AI) Assisted Real-time Adenoma Detection and Classification During Colonoscopies

This is a pragmatic, double-blind, randomized, controlled trial, to evaluate the effect of implementing a Computer-assisted detection (CADe) system within the routine clinical practice of Canadian healthcare institutions. The main hypothesis of this study is that the ADR in the operating room equipped with the GI genius CADe system will be significantly higher than the ADR in the ordinary operating room.

Participants needed: 1,596
Trial details
Age: 45-89Biological sex: AllType: InterventionalSponsor: Centre hospitalier de l'Université de Montréal (CHUM)Updated: Mar 5, 2025Locations: 1
Eligibility criteria

indication of undergoing a screening, surveillance, or diagnostic colonoscopy [+1]

Patients undergoing emergency colonoscopy [+1]