Atypical Teratoid/Rhabdoid Tumor (AT/RT)

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Review clinical trials related to Atypical Teratoid/Rhabdoid Tumor (AT/RT). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Safety and Efficacy of Vertebral Body-Sparing Craniospinal Irradiation With Proton Therapy in Pediatric Tumors

his is a single-center, prospective observational study in children and adolescents with central nervous system tumors who need whole-brain and whole-spine radiation therapy (craniospinal irradiation, CSI). The study uses proton therapy with a special vertebral body-sparing (VBS) technique to protect the front and center of the vertebrae, which helps preserve bone marrow function and growth. The main goals are to find safe dose limits for the vertebrae and check how often severe side effects occur. The study will also look at bone marrow preservation, spinal deformity, tumor control, survival, chemotherapy completion, neurocognitive function, quality of life, and growth and development for up to 5 years after treatment.

Participants needed: 38
Trial details
Age: 4-18Biological sex: AllType: ObservationalSponsor: Ruijin HospitalUpdated: May 15, 2026
Eligibility criteria

The patient's legal guardian voluntarily signs the written informed consent form... [+6]

Previous receipt of any form of spinal radiotherapy. [+6]