AV Block-2Nd Degree-Type 1

2

Review clinical trials related to AV Block-2Nd Degree-Type 1. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Efficacy and Safety of Micra AV2 Transcatheter Pacing System

A third generation, Micra AV2 is now available and proposes increased automaticity and improved AV synchrony algorithms based on computing model. The new algorithms permit the delivery of AV synchronous pacing, improving the automatic AV synchrony at faster heart rates between 80-100 bpm with a maximal upper tracking rate limit of 135 bpm (previously 115-120 bpm in the Micra AV1). Micra AV2 presents also a potential extended longevity of 15.6 years (increased by \> 44% in comparison of Micra AV1). Up to now, no clinical study has evaluated the efficacy and safety of Micra AV2 in a real-world setting. The focus of this study is to characterize chronic ambulatory AV synchrony in patients with high degree AV block and normal sinus rhythm implanted with a Micra AV2 as primary objective to evaluate AV synchrony during exercise as secondary objective.

Participants needed: 150
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Universitaire Ziekenhuizen KU LeuvenUpdated: Jan 21, 2026Locations: 1
Eligibility criteria

Voluntary written informed consent of the participant or their legally authorize... [+4]

Status: Recruiting

Cardioneuroablation for Recurrent Vasovagal Syncope and Bradyarrhythmias: The CNA-FWRD Registry

The CNA-FWRD Registry is an international prospective observational multicenter registry of patients with symptomatic vasovagal syncope and bradyarrhythmias managed under routine care by medical therapy and radiofrequency catheter ablation of ganglionated plexi or permanent pacemaker implantation.

Participants needed: 300
Trial details
Age: 18-60Biological sex: AllType: ObservationalSponsor: Rush University Medical CenterUpdated: Sep 18, 2025Locations: 1Duration: 3 Years
Eligibility criteria

symptomatic vasovagal syncope or symptomatic bradyarrhythmia refractory to behav... [+1]

age > 60 years [+10]