Status: Recruiting
Plasma Oxytocin Response to Oral Estrogens in Healthy Controls and AVP-Deficiency
The PHOENIX study aims to investigate whether oral estradiol valerate (EV) and ethinylestradiol (EE) can stimulate oxytocin (OXT) and neurophysin-1 (NP-1) release in humans. The goal is to assess their potential as a safe diagnostic stimulation test for oxytocin deficiency, particularly in patients with arginine vasopressin (AVP) deficiency.
Participants needed: 28
Trial details
Age: 18-50Biological sex: AllType: InterventionalSponsor: University Hospital, Basel, SwitzerlandUpdated: Jan 23, 2026Locations: 1
Eligibility criteria
Adult healthy controls [+5]
Participation in a trial with investigational drugs within 30 days [+23]