Health Trials

B-cell Non Hodgkin Lymphoma (NHL)

3

Review clinical trials related to B-cell Non Hodgkin Lymphoma (NHL). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

CD45BE-HSPC + CART-45 Cells

This is a phase 1, open-label, dose-finding study to assess the safety, feasibility, pharmacokinetics and preliminary efficacy of autologous base edited anti-CD45 CAR T cells (referred to as "CART-45 cells") following an autologous transplant of CD45 base edited hematopoietic stem and progenitor cells (referred to as "CD45BE-HSPC") in patients with relapsed or refractory hematologic malignancies.

Participants needed: 42
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: University of PennsylvaniaUpdated: Jun 10, 2026Locations: 1
Eligibility criteria

Patients must have either failed/relapsed after, or be ineligible for, prior com... [+11]

Active hepatitis B or hepatitis C infection [+12]

Read more
Status: Recruiting

A Clinical Study Exploring the Safety, Efficacy and Metabolic Kinetics of CT1182 Injection in Patients With Relapsed / Refractory Non Hodgkin Lymphoma

This study is a single arm, open label, dose exploring clinical study to evaluate the safety, efficacy, metabolic kinetics and pharmacodynamics of CT1182 cells in patients with relapsed / refractory B-cell non Hodgkin lymphoma (r/r B-NHL).

Participants needed: 24
Trial details
Phase: Early Phase 1Age: 18-75Biological sex: AllType: InterventionalSponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyUpdated: Apr 23, 2026Locations: 1
Eligibility criteria

voluntarily participate in clinical research; I fully understand and know this s... [+15]

pregnant or lactating women; [+21]

Read more