B Lymphoblastic Leukemia/Lymphoma

2

Review clinical trials related to B Lymphoblastic Leukemia/Lymphoma. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

A Clinical Study of Humanized CD19 CAR-T Cells With TLR2 for the Treatment of Adult Patients With Naive B-Cell Acute Lymphoblastic Leukemia/Lymphoma Who Are Intolerant to Intensive Chemotherapy

The purpose of this clinical trial is to tolerability and safety of humanized CD19 CAR-T therapy with TLR2 in adult patients with acute B lymphoblastic leukemia/lymphoma who cannot tolerate intense chemotherapy at initial treatment. Participants will receive a single infusion of CD19 CAR-T and complete follow-ups over the next three years.

Participants needed: 60
Trial details
Phase: Early Phase 1Age: 18-80Biological sex: AllType: InterventionalSponsor: Zhujiang HospitalUpdated: Jan 12, 2026
Eligibility criteria

Newly treated patients with acute B-lymphocytic leukaemia/lymphoma who are clini... [+6]

severe cardiac insufficiency, left ventricular ejection fraction <50%; [+13]

Status: Recruiting

The Safety and Efficacy of RD06-03 CART Cell Injection in Patients With R/R Acute B-lymphoblastic Leukemia

This study is designed to explore the safety and efficacy for patients with relapsed and/or refractory B-cell lymphoblastic leukemia.

Participants needed: 9
Trial details
Phase: Early Phase 1Age: 3-70Biological sex: AllType: InterventionalSponsor: Anhui Provincial HospitalUpdated: Jan 23, 2025Locations: 2
Eligibility criteria

Aged ≥3 and ≤70 years, gender and race unrestricted. [+4]

Suffering from genetic syndromes such as Fanconi anemia, Kostmann syndrome, Shwa... [+7]