Bell Palsy

12

Review clinical trials related to Bell Palsy. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Effect of Low Energy Extracorporeal Shockwave on Patients With Bell's Palsy

This study aims to investigate the effect of low energy extracorporeal shock wave therapy on patients with Bell's palsy.

Participants needed: 42
Trial details
Age: 45-55Biological sex: AllType: InterventionalSponsor: Cairo UniversityUpdated: Jun 22, 2026Locations: 1
Eligibility criteria

Patients with unilateral Bell's palsy (only lower motor neuron lesion). [+8]

Patients with a history of facial paralysis post-stroke. [+5]

Status: Not yet recruiting

Electroacupuncture With Two Pulse Patterns for Bell's Palsy Using Surface Electromyography Evaluation

This clinical trial is designed to evaluate the therapeutic effects of two EA parameter settings for Bell's palsy and to investigate the electromyographic characteristics of the disease. The main questions it aims to answer are: * Can continuous pulse pattern and intermittent pulse pattern of EA improve the symptoms of Bell's palsy? * Do continuous pulse pattern and intermittent pulse pattern of EA impact the electromyographic characteristics of facial muscles in patients with Bell's palsy? The researchers will evaluate the effects of continuous pulse pattern and intermittent pulse pattern in treating Bell's palsy by using surface electromyography as an objective indicator of assessment. The trial lasts for 4 weeks and the treatment period lasts for 4 weeks. Participants will: * receive sham EA, EA with a continuous pulse pattern or EA with an intermittent pulse pattern for 3 times weekly for 4 weeks (12 sessions in total). * receive assessment of symptom severity and social functioning on Day 0, end of week 2, end of week 4.

Participants needed: 111
Trial details
Age: 18-70Biological sex: AllType: InterventionalSponsor: The First Affiliated Hospital of Zhejiang Chinese Medical UniversityUpdated: Apr 30, 2026
Eligibility criteria

diagnosed clinically as BP, with imaging evidence (brain CT and/or MRI) excludin... [+3]

facial paralysis caused by other diseases [+8]

Status: Recruiting

Different Laser Frequencies on Neuropathic Outcomes in Patients With Bell's Palsy

this study was done to compare different laser frequencies on neuropathic outcomes in patients with Bell's palsy.

Participants needed: 80
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Kafrelsheikh UniversityUpdated: Apr 9, 2026Locations: 1
Eligibility criteria

Eighty subjects from both genders diagnosed with Bell's palsy will be recruited... [+4]

We will exclude patients who had central nervous system pathology, sensory loss... [+4]

Status: Recruiting

Efficacy of Prednisolone Versus Cerebrolysin in the Treatment of Bell's Palsy

Bell's palsy, a peripheral facial nerve paresis, is the most common disorder of the facial nerve and one of the most common mononeuropathies. Many patients with Bell's palsy will develop some complications such as synkinesis, crocodile tears and 'sweating' of the ear while eating Commonly used medications to treat Bell's palsy is Corticosteroids Cerebrolysin stimulates the regeneration of the nervous tissue with protective action we aim to study the efficacy of cerebrolycin in Bell's palsy

Participants needed: 90
Trial details
Phase: Phase 1, Phase 2Age: 18-60Biological sex: AllType: InterventionalSponsor: October 6 UniversityUpdated: Jul 31, 2025Locations: 1
Eligibility criteria

unilateral acute facial palsy of no identifiable cause

Recurrent facial Bell's palsy [+10]

Status: Not yet recruiting

Effectiveness of Electrical Stimulation With Mime Therapy Versus Electrical Stimulation With Proprioceptive Neuromuscular Facilitation on Improving Facial Asymmetry and Quality of Life in Patients With Bell's Palsy

To compare the effect of electrical stimulation with mime therapy versus electrical stimulation with proprioceptive neuromuscular facilitation on improving facial asymmetry and quality of life in patients with Bell's palsy.

Participants needed: 38
Trial details
Age: 25-45Biological sex: AllType: InterventionalSponsor: Shalamar Institute of Health SciencesUpdated: Jun 19, 2025
Eligibility criteria

Idiopathic Bell's Palsy Subacute and acute Bell's Palsy

UMNL facial palsy patient Non-compliant patient Patient with any psychiatric iss...

Status: Recruiting

Intradermal Acupuncture and Self-rehabilitation Program in Patients With Severe Bell's Palsy

This study aims to assess the effect of intradermal acupuncture(IA) and guided self-rehabilitation management program(GRMP) (either single or combined) for patients with severe Bell's Palsy.

Participants needed: 552
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Zhangjiagang First People's HospitalUpdated: Apr 30, 2025Locations: 1
Eligibility criteria

Patients diagnosed with Bell's palsy according to "Clinical Practice Guideline:... [+4]

Facial paralysis caused by acoustic neuroma, otitis media, mastoiditis, mumps, H... [+5]

Status: Recruiting

Evaluation of Cortisone Treatment in Children With Acute Facial Nerve Palsy

Acute facial nerve palsy occur in 10-20/100 000 children/year in Sweden. About 20 % of these children will have persistent symptoms with excessive tear secretion, drooling and social problems due to asymmetry in the face. Studies on cortisone treatment to adult patients with acute facial nerve palsy have shown beneficial effects, but no studies with strong quality have been performed in children. Investigators will perform a double-blind randomized placebo-controlled multicenter trial on children with acute facial nerve palsy. Participants will be recruited consecutively at 9-12 study centers in Sweden during 2019-2020. Oral cortisone (prednisolone) 1 mg/kg x 1 in 10 days (or placebo) will be started on admission. Clinical data, including recovery will be followed-up until 12 months. The primary outcome is defined as total recovery of the facial nerve palsy, measured with the House-Brackmann scale (grade 1) at 12-months follow-up. The overall purpose is to assess the utility of cortisone treatment given to children with acute facial nerve palsy in this study. If the total recovery rate is significantly improved in the prednisolone group as compared to the placebo group, prednisolone treatment will be introduced in clinical practice for children with acute facial nerve palsy in order to reduce the risk of persistent symptoms.

Participants needed: 500
Trial details
Phase: Phase 4Age: 1-17Biological sex: AllType: InterventionalSponsor: Dalarna County Council, SwedenUpdated: Feb 21, 2025Locations: 15
Eligibility criteria

1-17 years of age [+3]

Head trauma <1 month [+13]

Status: Recruiting

The Relationship Between Idiopathic Acute Peripheral Facial Paralysis and Homocysteine Level in Adult Patients

In the etıology of Idıopathıc Acute Perıpheral Facıal Palsy, known as bell palsy, many causes have been descrıbed, such as specıfıc ımmune, ıchemıc, ınfectıous and heredıal factors. ın our study, we have observed the blood homocysteıne level that causes thrombotıc dısorders ın paralysıs patıents.

Participants needed: 80
Trial details
Age: 18-80Biological sex: AllType: ObservationalSponsor: Murat AkınUpdated: Dec 19, 2024Locations: 3Duration: 2 Months
Eligibility criteria

Facial and ear trauma or tumor [+3]

Status: Recruiting

Laser Acupuncture for Idiopathic Bell's Palsy

Bell's palsy is characterized by acute, unilateral onset that compromises function and esthetics, exerting a considerable impact on the social, professional, and psychological aspects of the lives of affected individuals. The objective of this study was to determine whether laser acupuncture therapy could relieve symptoms in patients with Bell's palsy.

Participants needed: 360
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Beijing Tongren HospitalUpdated: Dec 13, 2024Locations: 1
Eligibility criteria

1. Patients diagnosed with idiopathic Bell's Palsy 2.Patients were eligible if t...

1. Serious mental illness or social problems, and neurological disorders, and sy...

Status: Recruiting

Screening for Prognostic Biomarkers of Severe Bell's Palsy in Adults

Bell's palsy (idiopathic peripheral facial palsy) is the most common cause of facial palsy, which is related to the inflammation of the facial nerve, possibly induced by herpesvirus reactivation. Its first-line treatment comprises corticosteroids, antiviral therapy and physiotherapy. In most severe cases (grade IV to VI on House-Brackmann scale), facial motricity may remain altered or develop synkinesis or post-paralytic spasm, thus tremendously affecting quality of life. To avoid potential complications, surgical facial nerve decompression could be proposed. To date, however, there are no means to predict if Bell's palsy will evolve with any complications or if the patient will recover entirely. Thus, the invasive facial nerve decompression is equally proposed to subjects who will develop the consequences as well as to subjects able to restore without surgical treatment. This study proposes to search for prognostic blood biomarkers related to the Bell's palsy recovery pattern. Adult patients with severe Bell's palsy will be proposed to have a blood sampling for proteomic analysis in the early stage of the disease. Then 125 biomarkers on a Peptiquant™ kit will be analysed by mass spectrometry, and prognostic biomarkers will be selected regarding to the clinical recovery of Bell's palsy

Participants needed: 130
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: University Hospital, MontpellierUpdated: Aug 20, 2024Locations: 1
Eligibility criteria

Severe Bell's palsy (House-Brackmann more or equal to IV) [+2]

Anti-inflammatoty, immunomodulating, immunosuppressive treatment [+10]

Status: Recruiting

Mime Therapy With and Without Neural Mobilization in Bell's Palsy.

To determine the Effects of Mime Therapy with and without Neural Mobilization on Facial symmetry, Synkinesis and Functional abilities in Patients with Bell's Palsy. It has been proven that Mime therapy is effective on activating muscles through articulation exercises, facial expression exercises, breathing exercises and facial massages which can alleviate synkinesis, enhance facial symmetry and promote facial functional abilities. On the other hand, facial neural mobilization has recently reported as a safe and effective adjunctive therapy for patients with Bell's palsy due to the facilitation of nerve gliding in the canal impacts by reducing nerve adherence dispersion of noxious inflammatory agents and increasing neural blood supply. So, by incorporating the Neural mobilization with Mime therapy, therapist may enhance overall facial symmetry, reduce the strain on the facial muscles and alleviate synkinesis. So, it may prove to be an upgraded treatment option for clinicians.

Participants needed: 32
Trial details
Age: 20-40Biological sex: AllType: InterventionalSponsor: Riphah International UniversityUpdated: Jun 14, 2024Locations: 1
Eligibility criteria

Not listed