Benign Gynecologic Neoplasm

2

Review clinical trials related to Benign Gynecologic Neoplasm. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

A Randomized Study Comparing Subtotal vs Total Hysterectomy Long Term Outcomes

The goal of this randomized clinical trial is to assess the outcomes of total laparoscopic hysterectomy vs subtotal laparoscopic hysterectomy + mini-laparotomy for uterine extraction for benign gynecological conditions in terms of change in quality of life at 36 months after surgery and patient's impression of improvement. The secondary objectives of the study are to assess any differences in terms of peri and postoperative outcomes (postoperative pain, blood loss, hospital stay, intraoperative or short and long-term postoperative complications, long term urinary, bowel and pelvic floor symptoms, prevalence of vaginal cuff dehiscence). Participants will fill the following questionnaires pre-operatively and at the follow up: * Short Form 36 (SF36), * Euro Quality of life 5D-3L (EQ 5D-3L) * Female Sexual Function Index (FSFI) * Patient Global Impression of Improvement (PGI-I) only during the follow-up period.

Participants needed: 500
Trial details
Age: 18-80Biological sex: FemaleType: InterventionalSponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCSUpdated: Sep 5, 2025Locations: 1
Eligibility criteria

Age>18 years [+1]

Uterine or adnexal pathology suspect for malignancy [+8]

Status: Recruiting

Efficacy and Safety Evaluation of Vi-sealer

This study's primary goal is to compare the efficacy and safety of the novel advanced hemostatic device(AHD), Vi-Sealer, with conventional AHDs in laparoscopic total hysterectomy for patients with benign gynecologic neoplasm.

Participants needed: 280
Trial details
Age: 20-65Biological sex: FemaleType: InterventionalSponsor: Hyun ParkUpdated: Oct 1, 2024Locations: 1
Eligibility criteria

Aged 20 to 65 years [+3]

Large uterus size over 16 weeks of gestational age [+6]