Beta-Amyloid

3

Review clinical trials related to Beta-Amyloid. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)

The purpose of this study is to assess the safety, tolerability, immunogenicity and pharmacodynamic effects of ACI-24.060 in subjects with prodromal Alzheimer's disease and in non-demented adults with Down syndrome.

Participants needed: 304
Trial details
Phase: Phase 1, Phase 2Age: 35-85Biological sex: AllType: InterventionalSponsor: AC Immune SAUpdated: May 29, 2026Locations: 26
Eligibility criteria

Age ≥50 and ≤85 years at screening. [+9]

Any unstable and/or clinically significant medical condition likely to hamper th... [+31]

Status: Recruiting

Beta Amyloid PET/CT in Various Aβ-Related Disease

To evaluate the potential usefulness of 18F-92/AV45, 11C-PIB positron emission tomography/computed tomography (PET/CT) for the diagnosis of primary and metastatic lesions in various Tau-related disease patients.

Participants needed: 500
Trial details
Age: 18-80Biological sex: AllType: ObservationalSponsor: Tianjin Medical UniversityUpdated: Jun 4, 2025Locations: 3Duration: 7 Days
Eligibility criteria

Not listed

Status: Recruiting

Association of Transcranial Alternating Current Stimulation with Digital Cognitive Training for Cognitive Remediation in Older Adults

BACKGROUND Cognitive decline in older adults, especially those who develop Mild Cognitive Impairment and Alzheimer's Disease, currently has limited options of pharmacological treatments, with modest efficacy. Digital Cognitive Training (DCT) and Transcranial Alternating Current Stimulation (tACS) are two promising tools for cognitive remediation in this population. In this exploratory study, we investigate feasibility, tolerability and preliminary effects of the association of both interventions in older adults with cognitive complaints. METHODS Older adults with cognitive complaints are being enrolled for this study, which comprises 5 daily sessions of 30 minutes of DCT using the BrainHQ platform while simultaneously receiving theta tACS (6Hz, 1.6mA) targeting the Left Dorsolateral Prefrontal Cortex.

Participants needed: 40
Trial details
Age: 50+Biological sex: AllType: InterventionalSponsor: Universidade Federal do Rio de JaneiroUpdated: Dec 13, 2024Locations: 1
Eligibility criteria

Healthy subjects over 50 years old, with cognitive complaints

Estimated Intelligence Quotient <80 [+8]