Bleomycin Adverse Reaction

2

Review clinical trials related to Bleomycin Adverse Reaction. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

The Effect of Reduced Bleomycin in Electrochemotherapy Treatment

The objective of this trial is to determine if reducing the chemotherapy dose in electrochemotherapy is equally effective as using the standard dose for treating various types of skin tumors. Electrochemotherapy involves administrating chemotherapy intravenously, followed shortly by a brief electrical pulse to the tumor. This pulses temporarily increases the tumor cells permeability, allowing the chemotherapy to enter more effectively. Participants will undergo a single session of electrochemotherapy with either half the standard chemotherapy dose or the full standard dose. The size of the cutaneous tumors will be measured before treatment and again three months after the treatment to compare their response in both groups. To monitor the tumors, as well as assess the adverse events and quality of life, participants must attend follow-up visits at two weeks, three months and twelve months. Additional visits may be scheduled at one, two, four and six months, if necessary, as determined by the clinician or the patient. Concentration of chemotherapy will be measured in blood samples and in samples from the treated tumor and normal skin.

Participants needed: 55
Trial details
Phase: Phase 4Age: 18+Biological sex: AllType: InterventionalSponsor: Julie GehlUpdated: Jan 23, 2025Locations: 2
Eligibility criteria

Trial subject > 18 years. [+9]

Pregnancy or lactation. All fertile women will have to deliver a negative pregna... [+5]

Status: Not yet recruiting

Comparison Between Diode Laser and Bleomycin in Treatment of Hemangioma

Assessment of the Effectiveness of Bleomycin Intralesional Injection and Diode Laser on Management of Infantile Hemangioma., with regard to : * Clinically based on Change in the Size and Color of Hemangioma. * Ultrasonography considering Vascularity ,Echogenicity , Height , and Morphology . * Comparison of Complications associated with Bleomycin and Diode Laser.

Participants needed: 30
Trial details
Age: 3-12Biological sex: AllType: ObservationalSponsor: Assiut UniversityUpdated: Jul 19, 2024
Eligibility criteria

Age between 3 Months and 1 Year old. [+1]

Younger than 3 Months or older than 1 Year. [+1]