Body Dysmorphic Disorder

4

Review clinical trials related to Body Dysmorphic Disorder. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Safety Behavior Fading Versus Progressive Muscle Relaxation for Appearance Concerns

The current study aims to explore the efficacy of a text message based safety behavior fading intervention compared to a progressive muscle relaxation intervention for appearance concerns.

Participants needed: 300
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Florida State UniversityUpdated: Jun 2, 2026Locations: 1
Eligibility criteria

being between the ages of 18 and 65 years old [+2]

changes in psychotropic medication in the last 4 weeks [+1]

Status: Recruiting

Individual Factors of CBT Underlying Success

The purpose of this study is to understand why some individuals respond fully to cognitive behavioral therapy and others do not, based on multiple sources of data such as neural, neurocognitive, clinical, and self-report data.

Participants needed: 160
Trial details
Age: 18-45Biological sex: AllType: InterventionalSponsor: University of WashingtonUpdated: Feb 17, 2026Locations: 1
Eligibility criteria

Men and women, age 18-45 [+6]

Score < 80 based on WRAT5 Word Reading Subtest [+1]

Status: Recruiting

Perceptual Abnormalities and Their Malleability in BDD

A core symptom of body dysmorphic disorder (BDD) is perceptual distortions for appearance, which contributes to poor insight and delusionality, limits engagement in treatment, and puts individuals at risk for relapse. Results from this study will provide a comprehensive mechanistic model of brain, behavioral, and emotional contributors to abnormal perceptual processing, as well as how malleable it is with visual modulation techniques. This will lay the groundwork for next-step translational perceptual retraining approaches.

Participants needed: 146
Trial details
Age: 18-40Biological sex: AllType: InterventionalSponsor: Centre for Addiction and Mental HealthUpdated: Nov 14, 2025Locations: 1
Eligibility criteria

males or females [+11]

concurrent major Axis I disorders including substance use disorders, aside from... [+16]

Status: Recruiting

When The Mirror Is Wrong

Body Dysmorphic Disorder (BDD) is a severe psychiatric condition characterized by persistent and intrusive preoccupations with perceived flaws in physical appearance, which are typically unnoticeable or appear minor to others. BDD is associated with significant psychological distress, functional impairment, and reduced quality of life. Despite its prevalence and clinical severity, BDD remains frequently underdiagnosed and misdiagnosed. While Cognitive Behavioural Therapy (CBT) and Selective Serotonin Reuptake Inhibitors (SSRIs) are currently considered standard treatments, emerging evidence suggests that third-wave psychotherapies, such as Acceptance and Commitment Therapy (ACT) and Compassion-Focused Interventions, may offer additional benefits. This project aims to advance clinical care and scientific understanding of BDD by developing, implementing, and evaluating the preliminary efficacy of MIND-over-MIRROR-a novel group-based psychological intervention integrating ACT and compassion-based strategies for individuals exhibiting high levels of BDD symptomatology. The intervention consists of eight weekly sessions and one follow-up booster session, delivered in an online or hybrid format. A randomized feasibility study will be conducted to examine the intervention's acceptability, practicality, and preliminary clinical efficacy in adults aged 18 to 65 years. A multi-method assessment framework will be employed, with self-report measures collected at baseline, post-intervention, and 3-month follow-up. Additionally, participants from experimental and control groups will report on their weekly BDD symptomatology. Participants in the intervention group who consent will also undergo computerized behavioural tasks and functional neuroimaging using functional near-infrared spectroscopy (fNIRS) to explore neural and cognitive correlates of treatment outcomes. Improvements are expected in core clinical outcomes, including BDD symptom severity, and it is hypothesized that changes in targeted psychological processes (e.g., self-compassion) will mediate these effects. This study will contribute novel and clinically relevant data regarding the feasibility and potential effectiveness of contextual behavioural therapies for BDD, with implications for both research and practice.

Participants needed: 16
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: University of CoimbraUpdated: Jun 29, 2025Locations: 1
Eligibility criteria

Aged between 18-65 years; [+2]

Pregnant; [+3]