Bone Healing

5

Review clinical trials related to Bone Healing. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Ultrasound Monitoring of Bone Healing in Ilizarov Bone Transport

This prospective study evaluates the role of ultrasound in assessing bony union during Ilizarov bone transport. Ultrasound findings will be compared with radiographic and clinical outcomes to determine its accuracy in detecting early bone healing and predicting mechanical stability. The study aims to establish ultrasound as a reliable, radiation-free tool to guide safe frame dynamization and removal.

Participants needed: 56
Trial details
Biological sex: AllType: ObservationalSponsor: Assiut UniversityUpdated: Apr 1, 2026
Eligibility criteria

Patients who will have Ilizarov bone transport,bone lengthening or corrective os...

Otherwise bone transport,bone lengthening or corrective osteotomy

Status: Not yet recruiting

Wound Healing Following Extraction and Ridge Preservation in Smokers and Non-smokers

The goal of this study is to evaluate bone wound healing following extraction and alveolar ridge preservation (bone graft and membrane) clinically, histologically and in relation to gene expression in smokers and non-smokers. Data from a small group of participants will be analyzed after age-matched subjects undergo extraction and alveolar ridge preservation prior to implant placement. The data obtained in this pilot study will be used to plan a full-fledged study involving a larger number of smoking and non-smoking participants to compare the two groups.

Participants needed: 12
Trial details
Age: 18-75Biological sex: AllType: ObservationalSponsor: Marquette UniversityUpdated: Jan 28, 2026Locations: 1
Eligibility criteria

Adult patients (18-75 years) [+7]

Uncontrolled periodontal disease [+3]

Status: Recruiting

Effects of Low-level Laser Therapy on Soft and Hard Tissue Healing After Impacted Mandibular Third Molar Extraction

Impacted lower third molar extraction is one of the most commonly performed dental procedures in daily practice. However, this is considered a relatively invasive procedure. During the surgery, dental surgeon must reflect a full-thickness flap, remove bone to expose the tooth, section and deliver the tooth. As a result, after surgery, patients often experience many complications, from swelling, pain, jaw tightness, etc. to alveolar bone loss, periodontal problems distal to the second molar, etc. Therefore, clinicians are always looking for additional therapies to minimize complications, helping patients have a more comfortable experience after wisdom tooth surgery. To date, placing grafting materials such as bone or other biological materials (growth factors, platelet-rich plasma, platelet-rich fibrin) into the tooth socket has been shown to be able to preserve the alveolar crest after extraction. However, these materials require preparation time, are costly, and have the risk of infection related to bone grafts. Meanwhile, low-level laser therapy (LLLT) is known as a safe, non-invasive therapy that can affect cell metabolism without causing tissue damage. This therapy has been widely applied in many fields of medicine in general and in dentistry in particular. Low-level lasers have been studied to help reduce swelling, pain, and jaw tightness after impacted lower wisdom teeth surgery. In vitro or in vivo studies evaluating the healing effect of low-level lasers have given very positive results. However, there is still a lack of scientific evidence to prove the healing effect of low-level lasers on human tooth extraction sockets. The study we conducted is a scientific study, in the field of Dentistry. This study aimed to evaluate the effectiveness of low-level laser on soft tissue and bone healing after surgical extraction of impacted lower third molars in a group of Vietnamese population.

Participants needed: 22
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of Medicine and Pharmacy at Ho Chi Minh CityUpdated: Nov 28, 2025Locations: 1
Eligibility criteria

Healthy patients (at least 18 years of age) have both jaws lower impacted third...

Status: Recruiting

Determinants of Bone Dimensional Changes After Extraction and Alveolar Ridge Preservation

The main purpose of the study is to measure and localize immediate post extraction changes i.e. socket expansion versus no width change along the socket wall and identify whether the immediate post-extraction ridge width condition (expansion or no change) is a determinant of buccolingual ridge width and height changes 4 months following extraction and ridge preservation.

Participants needed: 160
Trial details
Age: 18-75Biological sex: AllType: ObservationalSponsor: Marquette UniversityUpdated: Nov 17, 2025Locations: 1
Eligibility criteria

Adult patients (18-75 years) [+5]

Smoking [+4]

Status: Recruiting

ISQ Differences Between Different Implants in Post-extraction Sockets

Two different implants will be used in post-extraction sockets and ISQ will be recorded monthly from insertion moment to 12 months of follow up to understand if ISQ can be affected by implant macro design

Participants needed: 30
Trial details
Age: 18-99Biological sex: AllType: InterventionalSponsor: University of Rome Tor VergataUpdated: Mar 28, 2025Locations: 1
Eligibility criteria

Patients (at least 18 years old) presenting with failing tooth. [+5]

deep bite (severe II class) [+2]