Status: Recruiting
Effect of Large Neutral Amino Acids in Adults With Classical Phenylketonuria
The overall aim of this study is to evaluate LNAA treatment as a potential alternative to conventional dietary treatment for PKU. This study investigates the effects of LNAA treatment compared to the classic dietary treatment on cerebral dopamine synthesis in patients with classic PKU. We will assess LNAAs effectiveness on neurotransmitter synthesis, cognitive function, mental health, and safety, compared to the standard diet.
Participants needed: 30
Trial details
Age: 18-50Biological sex: AllType: InterventionalSponsor: Rigshospitalet, DenmarkUpdated: Apr 6, 2025Locations: 2
Eligibility criteria
Treatment initiation within the first month of life [+4]
Unable or unwilling to adhere to the requirements of the study [+7]