BRCA 1 /2 and / or HRD

1

Review clinical trials related to BRCA 1 /2 and / or HRD. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Study of SYN818 With Olaparib for the Treatment of Locally Advanced or Metastatic Solid Tumors

This interventional study will evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics and preliminary efficacy of SYN818 with Olaparib in adult patients with locally advanced or metastatic solid tumors

Participants needed: 110
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Hangzhou SynRx Therapeutics Biomedical Technology Co., LtdUpdated: Sep 5, 2025Locations: 2
Eligibility criteria

Having signed the written Informed Consent Form (ICF); [+8]

Previous or current use of DNA Polymerase Theta (POLQ) inhibitors; [+7]