BRCA1/2

2

Review clinical trials related to BRCA1/2. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Responses to Genetic Risk Modifier Testing Among Women With Pathogenic Variants in Breast Cancer Predisposition Genes

The purpose of this study is to describe how women with BRCA1/2 mutations react to genetic risk modifier testing, and to examine how they make decisions about their healthcare.

Participants needed: 806
Trial details
Age: 25+Biological sex: FemaleType: ObservationalSponsor: Memorial Sloan Kettering Cancer CenterUpdated: May 19, 2026Locations: 7
Eligibility criteria

Female patient, age 25 years or older (given that women under this age are not g... [+11]

Previous receipt of any prophylactic mastectomy. [+5]

Status: Recruiting

Study of How People Make Decisions About Prostate Cancer Risk

The purpose of this study is to learn how people with BRCA1/2 mutations respond to genetic risk modifier testing. The researchers will learn more about how people make choices about their health care, including about methods to screen for prostate cancer. Researchers are also doing this study to learn about how the genetic risk modifier test affects people's thoughts and feelings.

Participants needed: 150
Trial details
Age: 45-70Biological sex: MaleType: ObservationalSponsor: Memorial Sloan Kettering Cancer CenterUpdated: Apr 22, 2026Locations: 1
Eligibility criteria

Documentation of Disease [+4]

Major psychiatric illness or cognitive impairment that in the judgment of the st... [+4]