Breast Cancer Brain Metastases

2

Review clinical trials related to Breast Cancer Brain Metastases. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Efficacy and Safety of SPH4336 in Combination With Endocrine Therapy in Breast Cancer Patients With Brain Metastases.

This study evaluated the safety and efficacy of SPH4336 in combination with endocrine therapy in breast cancer Patients with brain metastases.

Participants needed: 52
Trial details
Phase: Phase 2Age: 18-75Biological sex: FemaleType: InterventionalSponsor: Shanghai Pharmaceuticals Holding Co., LtdUpdated: May 5, 2026Locations: 25
Eligibility criteria

Patients who voluntarily participate in this study, completely understand this s... [+6]

Inflammatory breast cancer. [+14]

Status: Recruiting

Study of SHR-A1811 Combined With Pyrotinib and Bevacizumab in Advanced Breast Cancer With Brain Metastasis

In phase Ib, our study is aimed to evaluate the safety and tolerance of SHR-A1811 combined with pyrotinib in breast cancer with brain metastasis, and confirm the recommended phase 2 dose combined with preliminary results of efficacy. In phase II, our study is aimed to evaluate the efficacy and safety of SHR-A1811 combined with pyrotinib and bevacizumab at RP2D in breast cancer with brain metastasis.

Participants needed: 74
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Fudan UniversityUpdated: Feb 6, 2025Locations: 1
Eligibility criteria

More than 18 years old; [+7]

Has leptomeningeal metastasis or cystic metastatic lesions confirmed by MRI or l... [+18]