Breast Cancer, Estrogen Receptor-Positive

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Review clinical trials related to Breast Cancer, Estrogen Receptor-Positive. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

A Study Evaluating the Efficacy and Safety of De Trastuzumab (T-DXd) in Combination with Immunotherapy for the Neoadjuvant Treatment of HR-positive HER2 Low-expressing Chinese Patients with Early-stage Breast Cancer

This is a prospective, open-label, multicenter, single-arm clinical study designed to compare the efficacy and safety of neoadjuvant treatment with T-DXd in combination with an immune checkpoint inhibitor in patients with primary intermediate- to high-risk HR-positive, HER2-overexpressing early-stage breast cancer.

Participants needed: 23
Trial details
Phase: Phase 2Age: 18-70Biological sex: FemaleType: InterventionalSponsor: Guangzhou Women and Children's Medical CenterUpdated: Dec 13, 2024
Eligibility criteria

Adults between the ages of 18 and 70 at the time of signing the informed consent... [+5]

Stage IV (metastatic) breast cancer and bilateral breast cancer [+3]

Status: Not yet recruiting

Validity of Brain Metastasis Risk Predictive Model in Hormone Positive Breast Cancer Patients

This study aims to validate a prediction model of brain metastasis risk for females with HR+ breast cancer by using variables collected at diagnosis.

Participants needed: 128
Trial details
Age: 18+Biological sex: FemaleType: ObservationalSponsor: Assiut UniversityUpdated: Dec 11, 2024
Eligibility criteria

Confirmed diagnosis of HR-positive primary invasive breast cancer.

Patients if they were diagnosed with brain metastases at the time of initial bre... [+4]