Status: Recruiting
Psychological State, Immunotherapy Response, and Multi-Omics Signatures in TNBC
This study aims to evaluate whether psychological status affects the response to neoadjuvant immunotherapy in triple-negative breast cancer (TNBC) and how it relates to immune changes during treatment. Participants will receive standard therapy, undergo psychological assessments, and provide blood and saliva samples for biomarker testing. By linking psychological status with immune profiles and treatment outcomes, the study seeks to clarify how mental state may influence immunotherapy effectiveness.
Participants needed: 120
Trial details
Age: 18-70Biological sex: FemaleType: ObservationalSponsor: Fudan UniversityUpdated: Dec 18, 2025Locations: 1Duration: 3 Months
Eligibility criteria
Age ≥ 18 years; [+4]
Presence of distant metastasis; [+7]