Breast Cancer Metastatic Breast Cancer

2

Review clinical trials related to Breast Cancer Metastatic Breast Cancer. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Quality of Life for Patients With Breast Cancer Brain Metastases and Leptomeningeal Disease

Central nervous system (CNS) metastases including breast cancer brain metastases (BCBMs) and leptomeningeal disease (LMD) are common affecting up to 30% of patients with metastatic breast cancer (MBC). The goal of this research is to understand symptom burden and quality of life trajectories in this population and how treatments guide care management decisions.

Participants needed: 200
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: University of California, San FranciscoUpdated: Jun 22, 2026Locations: 1
Eligibility criteria

Be male or female 18 years of age or older. [+4]

Status: Recruiting

Immunologic Targeting of ESR1 Receptor for Hormone Receptor Expressing Metastatic Breast Cancer

This is a pilot study to determine feasibility and safety of the combination of Dendritic Cell (DC1) vaccines and elacestrant in patients with hormone positive HER2 negative metastatic breast cancer.

Participants needed: 18
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: H. Lee Moffitt Cancer Center and Research InstituteUpdated: Dec 4, 2025Locations: 1
Eligibility criteria

Participants must have histologically or cytologically confirmed diagnosis of ho... [+14]

Stated willingness to comply with all study procedures and availability for the... [+18]