Health Trials

Breast Cancer With Brain Metastasis

2

Review clinical trials related to Breast Cancer With Brain Metastasis. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

T-DXd With or Without Neratinib for HER2 Positive Breast Cancer With Brain Metastasis

A phase II, open-label, multicenter, randomized controlled trial exploring the efficacy and safety of Trastuzumab Deruxtecan combined with or without Neratinib in HER2-positive breast cancer with brain metastasis

Participants needed: 202
Trial details
Phase: Phase 2Age: 18-70Biological sex: FemaleType: InterventionalSponsor: Fudan UniversityUpdated: Sep 3, 2025
Eligibility criteria

Female, aged 18-70 years old. [+13]

Transfer treatment exceeding 2 lines, or previous use of T-DXd or nalatinib. [+18]

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Status: Not yet recruiting

T-DXd With or Without Bevacizumab for HER2-low Breast Cancer With Brain Metastasis

A phase II, open-label, multicenter, randomized controlled trial exploring the efficacy and safety of Trastuzumab Deruxtecan combined with or without Bevicizumab in HER2-low breast cancer with brain metastasis.

Participants needed: 140
Trial details
Phase: Phase 2Age: 18-70Biological sex: FemaleType: InterventionalSponsor: Fudan UniversityUpdated: Sep 2, 2025Locations: 1
Eligibility criteria

ECOG score of 0 to 1. [+12]

Received more than 2 lines of chemotherapy. [+24]

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