Bullous Pseudophakic Keratopathy

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Review clinical trials related to Bullous Pseudophakic Keratopathy. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Effectiveness of PKP vs DSAEK in Terms of 2-year Postoperative Visual Acuity in Advanced BPK

This is an open-label multicenter randomised controlled clinical trial with 2 parallel arms with a 1:1 ratio. Patients meeting the eligibility criteria will be offered to participate in the study during an ophthalmology consultation. If they agree, they are randomised into one of the 2 arms, surgery is scheduled, and baseline visual acuity, quality of life, patient satisfaction, pain level, and central corneal thickness are recorded (inclusion visit). The following visits involve: the corneal transplant procedure (DSAEK or PKP depending on the randomisation) and follow-up visits at 1, 6, 12, and 24 months. At each visit, visual acuity, patient satisfaction, pain level and complications will be determined. At 6, 12, and 24 months, endothelial cell density, central corneal thickness and required optical correction will be measured. At 12 and 24 months, quality of life, will also be determined.

Participants needed: 334
Trial details
Age: 50+Biological sex: AllType: InterventionalSponsor: Centre Hospitalier Régional Metz-ThionvilleUpdated: Jun 24, 2026Locations: 11
Eligibility criteria

Is ≥ 50 years old. [+6]

Has a history of corneal transplant on either eye (i.e. the study surgery will b... [+6]