Burst Abdomen

2

Review clinical trials related to Burst Abdomen. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

NoPro - Norwegian Hernia Prophylaxis Study

A multicenter randomized controlled trial comparing midline laparotomy closures using the small-bite suture technique alone to those using the small-bite suture technique with an additional onlay prophylactic polypropylene mesh. The primary endpoint is the incidence of incisional hernias in both groups after one year.

Participants needed: 150
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Sykehuset Innlandet HFUpdated: Mar 5, 2025Locations: 1
Eligibility criteria

Surgery predominantly done my midline laparotomy [+4]

Age under 18 years [+6]

Status: Not yet recruiting

Using Vaccum Assisted Closure of Wound Instead of Primary Closure as Prophylactic Way Against Burst Abdomen

A vacuum-assisted closure (VAC) device also known as negative pressure wound therapy (NPWT), is a medical treatment used to promote wound healing, it involves using a specialized device to apply negative pressure (suction) to a wound, which helps to accelerate the healing process. Benefits : Improved Healing: By removing excess fluid and reducing edema, the VAC device promotes faster wound healing and tissue repair. Reduced Risk of Infection: The negative pressure helps to reduce bacterial load and create a more favorable environment for healing. Enhanced Perfusion: The suction can improve blood flow to the wound area, aiding in the delivery of nutrients and oxygen essential for healing. Granulation Tissue Formation: The therapy encourages the growth of new tissue (granulation tissue) which fills the wound and supports closure. Overall, VAC therapy is a valuable tool in modern wound care, particularly for complex or difficult-to-heal wounds. If you or someone you know is considering or using this therapy, it's important to follow the guidance of healthcare professionals to maximize its effectiveness and manage any potential risks. the study aim to evaluate patients , identify high risk ones , preparing to close wound of laparotomy with vaccum assisted device instead of primary closure with suturing till patient's general condition improve then delayed primary closure and comparing that to high risk patients who close wound primarily with suturing in terms of rate of burst abdomen …this is a randomized controlled trial

Participants needed: 100
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Assiut UniversityUpdated: Dec 13, 2024
Eligibility criteria

intraabdominal sepsis (wbc:>12000,HR>90,T>38,tachypnea and proven infection) Mal...

Patients having elective surgery Absence of intra abdominal sepsis Negative expl...