Cancer With A High Tumor Mutational Burden

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Review clinical trials related to Cancer With A High Tumor Mutational Burden. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Beta-only IL-2 ImmunoTherapY Study

This is a Phase 1/2, multi-center, open-label, dose-escalation and expansion study to evaluate safety and tolerability, PK, pharmacodynamic, and early signal of anti-tumor activity of MDNA11 alone or in combination with a checkpoint inhibitor in patients with advanced solid tumors.

Participants needed: 115
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Medicenna Therapeutics, Inc.Updated: Jul 9, 2025Locations: 27
Eligibility criteria

Aged at least 18 years (inclusive at the time of informed consent). [+8]

Prior systemic anti-cancer therapy including investigational agents within 4 wee... [+16]