Carbon Monoxide-induced Parkinsonism

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Review clinical trials related to Carbon Monoxide-induced Parkinsonism. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Carbon Monoxide Hyperbaric Oxygen With Steroid Therapy

Hyperbaric Oxygen Therapy (HBO) is routine treatment of carbon monoxide (CO) poisoning to prevent delayed neurological sequelae. This study looking to see if neurologic outcomes are improved with the addition of dexamethasone. CO poisoning can initiate a free radical mediated process that can instigate a demyelinating process resulting in long term neurological sequelae in some, but not all patients. In other demyelinating disorders, steroids are a part of first line treatment. HBO is already used for acute CO poisoning, so this pilot study will try to ascertain if the addition of steroids in concert with each hyperbaric oxygen session will yield improved outcomes.

Participants needed: 20
Trial details
Phase: Phase 1, Phase 2Age: 19+Biological sex: AllType: InterventionalSponsor: University of NebraskaUpdated: Apr 17, 2026Locations: 1
Eligibility criteria

Acute CO poisoning, intentional or non-intentional exposure, receiving HBO treat... [+2]

Mechanical ventilation [+3]