Carpometacarpal (CMC) Joint Arthritis

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Review clinical trials related to Carpometacarpal (CMC) Joint Arthritis. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Surgery for Thumb Base Osteoarthritis: Joint Replacement vs. Trapeziectomy

The goal of this clinical trial is to learn if the surgical method with total joint arthroplasty, (TOUCH joint prosthesis), is as good as or better than the traditional surgical method, trapezectomy, to treat thumb base joint osteoarthritis. The main questions it aims to answer are: Does surgery with total joint arthroplasty provide better power grip and pinch grip strength compared to traditional surgery? What is the long-term risk of complications for both methods? Which method is more cost-effective for the healthcare system? Researchers will compare total joint arthroplasty (TOUCH) to trapezectomy (a procedure where a bone in the thumb base is removed) to see which method provides the best results for the patient. Participants will: Be randomized to undergo either an operation with total joint arthroplasty or a trapezectomy. Undergo an initial evaluation and a health economic cost analysis after one year. Attend follow-up checkups at 2, 5, and 10 years post-surgery to evaluate long-term function and the durability of the prosthesis.

Participants needed: 84
Trial details
Age: 40-80Biological sex: AllType: InterventionalSponsor: Uppsala UniversityUpdated: Jun 25, 2026Locations: 2
Eligibility criteria

Age 40-80 years at inclusion [+5]

Previous surgery to thumb base or STT-joint [+5]

Status: Recruiting

Woodcasting Versus Thermoplast Splint in CMC Arthroplasty

This study is a prospective, randomized, nonblinded trial to evaluate patient preference in splints after having a carpometacarpal arthroplasty.

Participants needed: 26
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Foundation for Orthopaedic Research and EducationUpdated: Mar 17, 2025Locations: 1
Eligibility criteria

Patients over the age of 18 years old. [+3]

Pregnant Women [+1]