Cartilage Defect

1

Review clinical trials related to Cartilage Defect. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

A Study of Collagen Scaffold for the Repair of Elbow Cartilage Injury

The goal of this clinical trial is to test whether adding a collagen protein scaffold can improve cartilage repair in elbow joint injuries, compared to standard surgery alone. The study will enroll 90 patients (aged 18-55) with elbow cartilage damage who haven't responded to conservative treatments. The main questions it aims to answer are: * Does the collagen scaffold help regenerate better-quality cartilage (measured by MRI scans at 3 and 6 months)? * Do patients experience better pain relief and elbow function after this combined treatment? Researchers will compare two groups: * Experimental group : Receives microfracture surgery + collagen scaffold implant * Active Comparator group : Receives microfracture surgery alone Participants will: * Undergo arthroscopic surgery (either procedure) * Complete follow-up visits at 1 week, 1 month, 3 months, and 6 months * Have MRI scans and functional assessments * Report pain levels and daily activity limitations through questionnaires

Participants needed: 90
Trial details
Phase: Phase 3Age: 18-55Biological sex: AllType: InterventionalSponsor: Beijing Jishuitan HospitalUpdated: Sep 2, 2025Locations: 1
Eligibility criteria

Subjects are between the ages of 18 and 55 (including 18 and 55 years old); [+7]

Obvious narrowing of the elbow joint space or bone ankylosis formed between join... [+14]