Health Trials

Castration Resistant Prostate Cancer (CRPC)

2

Review clinical trials related to Castration Resistant Prostate Cancer (CRPC). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study to Investigate the Safety, Pharmacokinetics, and Preliminary Efficacy of IDE574 Therapy in Adult Participants With Advanced Solid Tumors

IDE574 is a synthetically manufactured small molecule inhibitor that co-targets the lysine acetyltransferase enzymes KAT6 and KAT7. The purpose of this study is to evaluate the safety, preliminary efficacy, pharmacokinetics (PK), and pharmacodynamics (PD) of IDE574 as monotherapy in participants with locally advanced or metastatic solid tumors and as combination therapy with fulvestrant in participants with advanced or metastatic ER+, HER2- breast cancer.

Participants needed: 160
Trial details
Phase: Phase 1Age: 18-99Biological sex: AllType: InterventionalSponsor: IDEAYA BiosciencesUpdated: Jun 16, 2026Locations: 11
Eligibility criteria

Part 1A - Participants with advanced or metastatic ER+, HER2- breast cancer, NSC... [+8]

Known symptomatic brain metastases or leptomeningeal metastasis [+8]

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Status: Recruiting

177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors

A Phase 1/2a Dose Escalation and Expansion Study of the Safety, Tolerability, and Preliminary Clinical Activity of 177LuBetaBart, a 177Lu-Labeled Anti-B7-H3 Monoclonal Antibody, in Patients with Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors

Participants needed: 61
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Radiopharm Theranostics, LtdUpdated: Mar 27, 2026Locations: 4
Eligibility criteria

Willing and able to provide informed consent prior to start of any study procedu... [+2]

Participants must have documented disease progression during or after their most... [+44]

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