Cataract and Fuchs Endothelial Corneal Dystrophy

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Review clinical trials related to Cataract and Fuchs Endothelial Corneal Dystrophy. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Trial Comparing Cataract Surgery With Triple-DMEK in Patients With Cataract and Fuchs Endothelial Corneal Dystrophy

The purpose of the study is to investigate whether there is a difference in BCVA in patients who receive one of the following two surgeries: intervention group (arm 1) cataract surgery alone and control group (arm 2) cataract surgery combined with removal of the diseased endothelial cells and the attached Descemet's membrane followed by transplantation of a healthy endothelial cell layer with attached Descemet's membrane ("triple-DMEK" group; comparator therapy). The secondary objectives are to compare the two surgical methods with regard to other visual functions and optical as well as morphological differences, to safety, to quality of life, and to safety.

Participants needed: 120
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of CologneUpdated: Feb 21, 2025Locations: 4
Eligibility criteria

Patients with FECD and nuclear cataract in study eye [+10]

Patients with ocular and/or systemic comorbidity affecting vision or clinically... [+10]