Status: Not yet recruiting
Clinical Study on the Safety and Efficacy of CD7-Targeted Chimeric Antigen Receptor (CAR) Gene-Modified T Cells for the Treatment of CD7-Positive Hematological Malignancies
This study is a single-arm, multicenter Investigator-Initiated Trial (IIT) clinical study. The primary objective is to evaluate the safety, pharmacokinetic characteristics, and preliminary efficacy of CAR-T cells in subjects with relapsed/refractory (r/r) CD7-positive hematological malignancies. The study plans to enroll 20 subjects, with the actual sample size to be determined based on real-world occurrence.
Participants needed: 28
Trial details
Age: 18-78Biological sex: AllType: InterventionalSponsor: Donghua ZhangUpdated: Jan 16, 2026Locations: 1
Eligibility criteria
Patients or their guardians understand and voluntarily sign the informed consent...
History of malignancy other than T-cell hematological malignancies within 5 year...