Status: Not yet recruiting
Efficacy and Cost-Effectiveness of Topical Vancomycin Powder in Preventing Pediatric Ventriculoperitoneal Shunt Infections Across Different Etiologies
Objectives * Primary: * To measure the reduction in VP shunt infection rates using topical vancomycin powder. * Secondary: * To compare efficacy across different Etiological Strata (Congenital, Post-hemorrhagic, post-inflammatory). * To analyze the microbiological profile of failed cases. * To compare the "Time-to-Infection" and shunt survival rates between the study and control groups using Kaplan-Meier analysis. * To evaluate the cost-effectiveness of TVP compared to the standard management and historical AIC data
Participants needed: 164
Trial details
Phase: Phase 4Age: 1-18Biological sex: AllType: InterventionalSponsor: Assiut UniversityUpdated: Apr 23, 2026Locations: 1
Eligibility criteria
Age Range: Paediatric patients from birth (neonates) up to 18 years of age. [+3]
Tumor-related Hydrocephalus: Due to the impact of malignancy, chemotherapy-induc... [+6]