Health Trials

Checkpoint Inhibitor

2

Review clinical trials related to Checkpoint Inhibitor. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Checkpoint Inhibitor Associated Diabetes Mellitus: Early Recognition and Treatment (CERT) Project: A Pilot Study

To find out if taking a drug called infliximab (the "study drug") is safe and effective in reversing insulin dependence in CIADM.

Participants needed: 14
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: M.D. Anderson Cancer CenterUpdated: Jun 23, 2026Locations: 1
Eligibility criteria

New onset diabetes≥ 200 mg/dl and/or A1c ≥6.5 OR [+9]

Participants already on insulin for pre-existing type 1 or type 2 diabetes. [+15]

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Status: Not yet recruiting

SARS-CoV-2 mRNA Vaccination in Patients With Hepatocellular Carcinoma Treated With Immune Checkpoint Inhibitors

A multicenter retrospective cohort analysis in Austria Primary Objective: To assess whether receiving an mRNA COVID-19 vaccine within 3 months before starting ICI (Immune checkpoint inhibitors) therapy improves best overall response (mRECIST) in HCC (hepatocellular carcinoma). Secondary Objectives: Evaluate whether vaccination within 1 or 3 months affects OS (overall survival) , PFS (Progression free survival)), or TTP (Time to progression); compare outcomes by vaccination status, vaccine type, and prior infection; explore modification by cirrhosis severity and tumor characteristics; and assess safety (irAEs, steroid use, toxicity-related discontinuation).

Participants needed: 200
Trial details
Biological sex: AllType: ObservationalSponsor: Medical University of GrazUpdated: Jan 14, 2026Locations: 5
Eligibility criteria

Age ≥ 18 years [+4]

Missing key clinical data required for main analyses (e.g. survival status, date...

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