Chemobrain

2

Review clinical trials related to Chemobrain. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Cognitive Impact Associated With Surgery For Gastric Or Esophageal Cancer

The primary objective of this observational study is to investigate the incidence of Post Operative Delirium (POD) after gastroesophageal cancer surgery. Secondary objectives are to investigate the relationship between POD, preoperative depression, frailty, quality of life, malnutrition and sarcopenia. Participants identified with POD will be asked (at the routine follow-up meeting after surgery) to participate in an qualitative interview, in order to understand the participant's experience of postoperative delirium. The main objective aims to answer: What is the incidence of POD after gastroesophageal cancer surgery.

Participants needed: 130
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Karolinska InstitutetUpdated: Jul 2, 2025Locations: 1Duration: 6 Months
Eligibility criteria

Patients diagnosed with esophageal or gastric cancer, treated with (or without)... [+3]

Patients with preoperative cognitive dysfunction such as dementia. [+4]

Status: Not yet recruiting

Cognitive Impairment in Treated Breast Cancer Survivors: Possible Approaches

The investigators aim is to conduct a prospective study with three arms, involving non-metastatic breast cancer patients who underwent chemotherapy as part of their treatment and were on a form of hormone therapy at the time of study inclusion. The trial consists of identifying the presence of cognitive decline and following up on methods of preventing its accentuation. The goal of this clinical trial is to assess if psychoeducation and cognitive stimulation work to decrease the intensity of cognitive impairment. It aims to answer the following main questions: * The implementation of such interventions improves both the dysfunction quantified by objective tests but also the individual's perception of it. * The implementation changes the patients' quality of life. Researchers will compare three study groups, each with instructions to complete one of the related 12-week programs, to see if there are any changes. Depending on the group in which the patient was randomly assigned, the interventions are : * First group - will engage in exercises like sudoku, word games, and painting by numbers for 30 minutes per day, three days per week, for a duration of 12 weeks * the second group will engage in exercises like sudoku, word games, and painting by numbers for 30 minutes per day, three days per week, for a duration of 12 weeks and also hold open group meetings for psychoeducation (1 meeting every 2 weeks, 6 meetings in total). * Group 3 is considered a control group, consisting of people who maintained their lifestyle up until their inclusion in the study without following additional measures

Participants needed: 120
Trial details
Age: 18+Biological sex: FemaleType: InterventionalSponsor: Grigore T. Popa University of Medicine and PharmacyUpdated: Oct 30, 2024
Eligibility criteria

female patients aged 18 years or older [+7]

history of neoplasia other than breast cancer [+6]