Health Trials

Chronic Hepatitis D

2

Review clinical trials related to Chronic Hepatitis D. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Study to Evaluate Switching to Brelovitug for the Treatment of CHD in Participants Receiving Bulevirtide

This is a Phase 2b/3, randomized, open-label, multicenter trial evaluating the efficacy and safety of switching from bulevirtide to brelovitug for the treatment of chronic hepatitis Delta infection (CHD).

Participants needed: 120
Trial details
Phase: Phase 2, Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Mirum Pharmaceuticals, Inc.Updated: Jun 29, 2026Locations: 35
Eligibility criteria

Willing and able to provide written informed consent. [+4]

Evidence of decompensated liver disease (e.g., CTP Class B or C, history of hepa... [+4]

Read more
Status: Recruiting

Study to Evaluate Efficacy, Safety and Biomarkers of Bulevirtide Treatment in Chronic Hepatitis D Patients

The aim is to assess the efficacy and specific safety in an observational study of patients with Chronic hepatitis D (CHD) with prospective follow-up, with antiviral treatment of 2 mg Bulevirtide (BLV) +/- PEG-IFNα-2a and +/- NA given as part of the patient's routine medical care. Also, explorative endpoints of biomarkers in peripheral blood, saliva, fecal sample and/or intrahepatic markers/signatures, and quality of life outcomes will be assessed.

Participants needed: 400
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Karolinska University HospitalUpdated: Sep 29, 2023Locations: 1
Eligibility criteria

Age > 18 years [+9]

Any contra-indications to treatment with BLV, including any intolerance or hyper... [+3]

Read more