Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

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Review clinical trials related to Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

A Study to Evaluate MTM-H-001 Injection in Adult Participants With Relapsed or Refractory B-cell Malignancies

This is an investigator-initiated, open-label, single-arm, dose-escalation and dose-expansion study to evaluate the safety, tolerability, PK, PD, and preliminary efficacy of MTM-H-001 in adult participants with relapsed/refractory (R/R) B-cell malignancies.

Participants needed: 69
Trial details
Age: 18-75Biological sex: AllType: InterventionalSponsor: Cancer Institute and Hospital, Chinese Academy of Medical SciencesUpdated: Mar 17, 2026Locations: 1
Eligibility criteria

Male or female, aged 18 - 75 years old (inclusive); [+12]

B-NHL participants with a history of Richter's transformation of chronic lymphoc... [+15]

Status: Recruiting

A Safety and Efficacy Study Evaluating CTX112 in Subjects With Relapsed or Refractory B-Cell Malignancies

This is an open-label, multicenter, Phase 1/2 study evaluating the safety and efficacy of CTX112™ in subjects with relapsed or refractory B-cell malignancies.

Participants needed: 120
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: CRISPR Therapeutics AGUpdated: Nov 14, 2025Locations: 7
Eligibility criteria

Age ≥18 years. [+4]

Prior allogeneic hematopoietic stem cell transplant (HSCT). [+8]