Status: Recruiting
Allogeneic Hematopoietic Cell Transplantation From HLA-matched Donor After Flu-Mel-PTCy Versus Flu-Mel-ATG Reduced-intensity Conditioning
The present project aims at comparing two conditioning regimens (FM-PTCy vs FM-ATG). The hypothesis is that one or the two regimens will lead to a 2-year cGRFS rate improvement from 30% (the cGRFS rate with FM without ATG/PTCy) to 45% (Pick-a-winner phase 2 randomized study).
Participants needed: 114
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: University of LiegeUpdated: Oct 12, 2022Locations: 10
Eligibility criteria
AML in morphological CR or not in morphological CR but not rapidly progressing (... [+23]
Any condition not fulfilling inclusion criteria; [+15]