Health Trials

Chronic Myelomonocytic Leukemia-2

3

Review clinical trials related to Chronic Myelomonocytic Leukemia-2. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

This is a Phase 1, multi-center, open-label study with a dose-escalation phase (Phase 1a) and a cohort expansion phase (Phase 1b), to evaluate the safety, tolerability, and PK profile of LP-118 under a once daily oral dosing schedule in up to 100 subjects.

Participants needed: 100
Trial details
Phase: Phase 1Age: 13+Biological sex: AllType: InterventionalSponsor: Newave Pharmaceutical IncUpdated: May 5, 2026Locations: 8
Eligibility criteria

Relapsed or refractory low risk tumor lysis CLL/SLL subjects (ALC < 25 x 109 cel... [+43]

Subjects who have undergone autologous/allogeneic hematopoietic stem cell transp... [+28]

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Status: Recruiting

A Phase 1 Study of STX-0712 in Patients With Advanced Hematological Malignancies (CMML and AML)

This is a first-in-human, multicenter, open-label, phase 1 study to evaluate the safety, PK, PD and preliminary efficacy of STX-0712 in patients with advanced CMML and AML for whom there are no further treatment options known to confer clinical benefit.

Participants needed: 105
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Solu Therapeutics, IncUpdated: Feb 9, 2026Locations: 7
Eligibility criteria

Refractory/resistant CMML, defined as: Diagnosis of CMML 1 or 2; and has not res... [+7]

Has any of the following disease-specific conditions: For CMML: Myelodysplastic... [+15]

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Status: Recruiting

Unrelated Umbilical Cord Blood Stem Cell Combined With Azacitidine Based Treatment for Advanced MDS,CMML-2 and sAML

This research is being done to study the efficacy and safety of unrelated umbilical cord blood stem cell microtransplantation combined with azacitidine(AZA) based treatment for advanced myelodysplastic syndromes(MDS), Chronic myelomonocytic leukemia-2(CMML-2) and secondary acute myeloid leukemia(sAML). The study protocol involved unrelated umbilical cord blood stem cell combined with azacitidine based treatment, which including azacitidine alone and azacitidine plus a targeted agent or chemotherapy agent.

Participants needed: 50
Trial details
Phase: Phase 1, Phase 2Age: 18-80Biological sex: AllType: InterventionalSponsor: The First Affiliated Hospital with Nanjing Medical UniversityUpdated: Oct 18, 2022Locations: 1
Eligibility criteria

MDS patients diagnosed due to bone marrow morphology and immunophenotyping (met... [+8]

BCR/ABL positive chronic myelogenous leukemia, primary myelofibrosis, polycythem... [+17]

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